Search Result "P-gp."


11C-verapamil to Assess P-gp Function in Human Brain During Aging,Depression and Neurodegenerative Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1775-1784
Author(s): A. L. Bartels, O. L. de Klerk, R. Kortekaas, J. J. de Vries, K. L. Leenders

Using PET Studies of P-gp Function to Elucidate Mechanisms Underlying the Disposition of Drugs

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1799-1809
Author(s): Stina Syvanen, Margareta Hammarlund-Udenaes

The Structure and Functions of P-Glycoprotein

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 8 Year: 2010 Page: 786-800
Author(s): Y. Li, H. Yuan, K. Yang, W. Xu, W. Tang, X. Li

Substrates, Inhibitors and Activators of P-glycoprotein: Candidates for Radiolabeling and Imaging Perspectives

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1703-1714
Author(s): Nicola A. Colabufo, Francesco Berardi, Maria Grazia Perrone, Elena Capparelli, Mariangela Cantore, Carmela Inglese, Roberto Perrone

Carbon-11 Labeled Tracers for In Vivo Imaging of P-Glycoprotein Function: Kinetics, Advantages and Disadvantages

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1820-1833
Author(s): Gert Luurtsema, Joost Verbeek, Mark Lubberink, Adriaan A. Lammertsma, Rudi Dierckx, Philip Elsinga, Albert D. Windhorst, Aren van Waarde

Interplay of Metabolism and Transport in Determining Oral Drug Absorption and Gut Wall Metabolism: A Simulation Assessment Using the “Advanced Dissolution, Absorption, Metabolism (ADAM)” Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 716-729
Author(s): A. S. Darwich, S. Neuhoff, M. Jamei, A. Rostami-Hodjegan

Transporters in the Brain Endothelial Barrier

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2010 Page: 1125-1138
Author(s): M. Ueno, T. Nakagawa, B. Wu, M. Onodera, C.-l. Huang, T. Kusaka, N. Araki, H. Sakamoto

Evaluation of [11C]S14506 and [18F]S14506 in Rat and Monkey as Agonist PET Radioligands for Brain 5-HT1A Receptors

Journal: Current Radiopharmaceuticals
Volume: 3 Issue: 1 Year: 2010 Page: 9-18
Author(s): Shuiyu Lu, Jeih-San Liow, Sami S. Zoghbi, Jinsoo Hong, Robert B. Innis, Victor W. Pike

Structural Contributions of Substrates to their Binding to P-Glycoprotein. A TOPSMODE Approach

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 2 Year: 2010 Page: 2676-2709
Author(s): Ernesto Estrada, Enrique Molina, Delvin Nodarse, Eugenio Uriarte

P-Glycoprotein and Breast Cancer Resistance Protein Affect Disposition of Tandutinib, A Tyrosine Kinase Inhibitor

Journal: Drug Metabolism Letters
Volume: 4 Issue: 4 Year: 2010 Page: 202-212
Author(s): Johnny J. Yang, Mark N. Milton, Shaoxia Yu, Mingxiang Liao, Ning Liu, Jing-Tao Wu, Liang-Shang Gan, Suresh K. Balani, Frank W. Lee, Shimoga Prakash, Cindy Q. Xia

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