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A Molecular Guidance System Based Upon Target Genes, Nuclear Receptors and Ligands Applied to Drug Discovery and Prediction of Toxicity

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1252-1264
Author(s): Virendra B. Mahesh, Neil Sidell, Douglas E. Ewing, Edwin D. Bransome Jr., Lawrence B. Hendry

Novel Orphan Nuclear Receptors-Coregulator Interactions Controlling Anti-Cancer Drug Metabolism

Journal: Current Drug Metabolism
Volume: 9 Issue: 7 Year: 2008 Page: 611-613
Author(s): Radharani Gollamudi, Divya Gupta, Sanjay Goel, Sridhar Mani

Nuclear Imaging of Prostate Cancer with Gastrin-Releasing-Peptide- Receptor Targeted Radiopharmaceuticals

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 2 Year: 2008 Page: 3033-3047
Author(s): H. J.K. Ananias, I. J. de Jong, R. A. Dierckx, C. van de Wiele, W. Helfrich, P. H. Elsinga

Nuclear Receptors as Potential Molecular Targets in Cholesterol Accumulation Conditions: Insights from Evidence on Hepatic Cholesterol Degradation and Gallstone Disease in Humans

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 2 Year: 2008 Page: 2271-2284
Author(s): M. Bertolotti, C. Gabbi, C. Anzivino, L. Carulli, P. Loria, N. Carulli

Bile Acids and Derivatives, Their Nuclear Receptors FXR, PXR and Ligands: Role in Health and Disease and Their Therapeutic Potential

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 8 Issue: 5 Year: 2008 Page: 540-563
Author(s): Amazia Zimber, Christian Gespach

Synthesis of a Novel Series of 8-HETE Analogs and their Biological Evaluation Towards the PPAR Nuclear Receptors

Journal: Letters in Drug Design & Discovery
Volume: 5 Issue: 8 Year: 2008 Page: 503-511
Author(s): Melanie Liutkus, Catherine Dacquet, Valerie Audinot-Bouchez, Jean Boutin, Daniel-Henri Caignard, Alain Ktorza, Rene Gree

Induction of Nuclear Receptors and Drug Resistance in the Brain Microvascular Endothelial Cells Treated with Antiepileptic Drugs

Journal: Current Neurovascular Research
Volume: 5 Issue: 2 Year: 2008 Page: 82-92
Author(s): Laura Lombardo, Rosalia Pellitteri, Michael Balazy, Venera Cardile

A Miniaturized Glucocorticoid Receptor Translocation Assay Using Enzymatic Fragment Complementation Evaluated with qHTS

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 7 Year: 2008 Page: 545-559
Author(s): Ping Jun Zhu, Wei Zheng, Douglas S. Auld, Ajit Jadhav, Ryan MacArthur, Keith R. Olson, Kun Peng, Hyna Dotimas, Christopher P. Austin, James Inglese

CRM1-Mediated Nuclear Export of Proteins and Drug Resistance in Cancer

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 2 Year: 2008 Page: 2648-2655
Author(s): Joel G. Turner, Daniel M. Sullivan

Gene Expression Profiles in Breast Cancer to Identify Estrogen Receptor Target Genes

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 5 Year: 2008 Page: 448-454
Author(s): M. A. Nagai, M. M. Brentani

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