Search Result "IC50"


A Transcellular Assay to Assess the P-gp Inhibition in Early Stage of Drug Development

Journal: Drug Metabolism Letters
Volume: 6 Issue: 4 Year: 2012 Page: 285-291
Author(s): Jan-Shiang Taur, Edgar L. Schuck, Nancy Y. Wong

Synthesis and β-Glucuronidase Inhibitory Potential of Benzimidazole Derivatives

Journal: Medicinal Chemistry
Volume: 8 Issue: 3 Year: 2012 Page: 421-427
Author(s): Khalid Mohammed Khan,Momin Khan,Nida Ambreen,Fazal Rahim,Shagufta Naureen,Shahnaz Perveen,M. Iqbal Choudhary,Wolfgang Voelter

Acylhydrazide Schiff Bases: DPPH Radical and Superoxide Anion Scavengers

Journal: Medicinal Chemistry
Volume: 8 Issue: 4 Year: 2012 Page: 705-710
Author(s): Khalid Mohammed Khan,Muhammad Taha,Farzana Naz,Salman Siddiqui,Sajjad Ali,Fazal Rahim,Shahnaz Perveen,M. Iqbal Choudhary

2,4,6-Trichlorophenylhydrazine Schiff Bases as DPPH Radical and Super Oxide Anion Scavengers

Journal: Medicinal Chemistry
Volume: 8 Issue: 3 Year: 2012 Page: 452-461
Author(s): Khalid Mohammed Khan,Zarbad Shah,Viqar Uddin Ahmad,Momin Khan,Muhammad Taha,Fazal Rahim,Sajjad Ali,Nida Ambreen,Shahnaz Perveen,M. Iqbal Choudhary,Wolfgang Voelter

Identification of LOGP Values and Electronegativities As Structural Insights to Model Inhibitory Activity of HIV-1 Capsid Inhibitors - A SVM and MLR Aided QSAR Studies

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 16 Year: 2012 Page: 1763-1774
Author(s): Nishant Sharma,K.R. Ethiraj,Mukesh Yadav,Anuraj Nayarisseri S,Mona Chaurasiya,Raju Naik Vankudavath,K. Rajender Rao

Synergistic Activities of a Silver(I) Glutamic Acid Complex and Reactive Oxygen Species (ROS): A Novel Antimicrobial and Chemotherapeutic Agent

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 21 Year: 2012 Page: 3635-3640
Author(s): K. I. Batarseh,M. A. Smith

In Vitro Activity Against Trypanosoma cruzi and Leishmania chagasi Parasites of 2,4-Diaryl 1,2,3,4-Tetrahydroquinoline Derivatives

Journal: Letters in Drug Design & Discovery
Volume: 9 Issue: 8 Year: 2012 Page: 802-808
Author(s): Arnold R. Romero Bohorquez,Patricia Escobar Rivero,Sandra M. Leal,Vladimir V. Kouznetsov

In Vitro Inhibition of Key Enzymes Related to Diabetes by the Aqueous Extracts of Some Fruits of West Bengal, India

Journal: Current Nutrition & Food Science
Volume: 8 Issue: 1 Year: 2012 Page: 19-24
Author(s): Susmita Das, Sukriti Das, Bratati De

Fig Latex (Ficus carica L. cultivar Dottato) in Combination with UV Irradiation Decreases the Viability of A375 Melanoma Cells In Vitro

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 12 Issue: 8 Year: 2012 Page: 959-965
Author(s): Giulio Menichini,Carmine Alfano,Eugenio Provenzano,Mariangela Marrelli,Giancarlo A. Statti,Francesco Somma,Francesco Menichini,Filomena Conforti

Evaluation of Time-Dependent Cytochrome P450 Inhibition in a High-Throughput, Automated Assay: Introducing a Novel Area Under the Curve Shift Approach

Journal: Drug Metabolism Letters
Volume: 6 Issue: 1 Year: 2012 Page: 43-53
Author(s): Sophie Mukadam, Suzanne Tay, Daniel Tran, Leslie Wang, Erlie M. Delarosa, S. Cyrus Khojasteh, Jason S. Halladay, Jane R. Kenny

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