Search Result "HDAC"


Review Article

HDACs and HDAC Inhibitors in Urothelial Carcinoma – Perspectives for an Antineoplastic Treatment

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 37 Year: 2017 Page: 4151-4165
Author(s): Maria Pinkerneil,Michele J. Hoffmann,Wolfgang A. Schulz,Gunter Niegisch

Review Article

Role of Histone Deacetylases (HDACs) in Epilepsy and Epileptogenesis

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 3 Year: 2017 Page: 5546-5562
Author(s):

Review Article

Medicinal Chemistry Insights into Novel HDAC Inhibitors: An Updated Patent Review (2012-2016)

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 12 Issue: 1 Year: 2017 Page: 16-34
Author(s): Peng Zhan, Xueshun Wang, Xinyong Liu, Takayoshi Suzuki

Research Article

Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 4 Year: 2017 Page: 441-459
Author(s): Maurizio Taddei,Manuela Rodriquez,Antonello Petrella,Caterina Fattorusso,Luca Rastrelli,Eduardo Sobarzo-Sánchez,Ettore Novellino,Anna Maria D`Ursi,Mario Scrima,Manuela Grimaldi,Marco Persico,Valentina Bizzarro,Elena Cini,Ilaria Moronese,Rosario Randino

Research Article

Synthesis, Enzyme Assays and Molecular Docking Studies of Fluorina ted Bioisosteres of Santacruzamate A as Potential HDAC Tracers

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 7 Year: 2017 Page: 787-797
Author(s): Muneer Ahamed, Koen Vermeulen, Michael Schnekenburger, Lise Roman Moltzau, Finn Olav Levy, Janos Marton, Mathy Froeyen, Dag Erlend Olberg, Marc Diederich, Guy Bormans

Research Article

Molecular Simulation and Activity Studies of Oxametacin as an HDAC Inhibitor

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 11 Year: 2017 Page: 1277-1282
Author(s): Fanbo Jing,Lei Zhang,Yepeng Luan,Jiang Bian

Review Article

Preclinical and Clinical Studies of Chidamide (CS055/HBI-8000), An Orally Available Subtype-selective HDAC Inhibitor for Cancer Therapy

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 17 Issue: 6 Year: 2017 Page: 802-812
Author(s): Shuai Gao,Xiaoyang Li,Jie Zang,Wenfang Xu,Yingjie Zhang

Review Article

Progress in the Discovery of Macrocyclic Histone Deacetylase Inhibitors for the Treatment of Cancer

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 37 Year: 2017 Page: 4166-4179
Author(s): Kai Cheng,Siyu Li,Chenzhong Liao

Review Article

Potential Application of 5-Aryl-Substituted 2-Aminobenzamide Type of HDAC1/2- Selective Inhibitors to Pharmaceuticals

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 4 Year: 2017 Page: 6149-6159
Author(s): Shinichi Uesato,Yoshiyuki Hirata,Tsutomu Sasaki

Review Article

Plant Derived Inhibitor Sulforaphane in Combinatorial Therapy Against Therapeutically Challenging Pancreatic Cancer

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2017 Page: 365-373
Author(s): Shabir Ahmad Ganai,Romana Rashid,Ehsaan Abdullah,Mohammad Altaf

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