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From Fragment Screening to Potent Binders: Strategies for Fragment-to-Lead Evolution

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 9 Issue: 8 Year: 2009 Page: 956-961
Author(s): Krystian Eitner, Uwe Koch

Novel MK2 Inhibitors by Fragment Screening

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 7 Year: 2009 Page: 697-703
Author(s): Oliver Keminer, Joachim Kraemer, Jan Kahmann, Ina Sternberger, Christoph Scheich, Joern Jungmann, Sabine Schaertl, Dirk Winkler, Osamu Ichihara, Mark Whittaker, Dirk Ullmann, Thomas Hesterkamp

Fragment Library Screening and Lead Characterization Using SPR Biosensors

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1725-1735
Author(s): U. Helena Danielson

Target Immobilization and NMR Screening of Fragments in Early Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1736-1745
Author(s): Gregg Siegal, Johan G. Hollander

Fragment-Based Discovery of Inhibitors of Protein Kinase B

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1705-1717
Author(s): Thomas G. Davies, Steven J. Woodhead, Ian Collins

The Effect of Post-Translational and Process-Induced Modifications on the Multistage Gas-Phase Fragmentation Reactions of Protonated Peptides

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 2 Year: 2009 Page: 175-184
Author(s): Jennifer M. Froelich, Gavin E. Reid

Fragment-Based Cocktail Crystallography by the Medical Structural Genomics of Pathogenic Protozoa Consortium

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1678-1687
Author(s): Christophe L.M.J. Verlinde, Erkang Fan, Sayaka Shibata, Zhongsheng Zhang, Zhihua Sun, Wei Deng, Jennifer Ross, Jessica Kim, Liren Xiao, Tracy L. Arakaki, Jurgen Bosch, Jonathan M. Caruthers, Eric T. Larson, Isolde LeTrong, Alberto Napuli, Angela Kelley, Natasha Mueller, Frank Zucker, Wesley C. Van Voorhis, Frederick S. Buckner, Ethan A. Merritt, Wim G.J. Hol

β-Endorphin Fragments DTγE and DEγE Reduced Morphine Inhibition of Electrically-Induced Contractions and Opiate Withdrawal

Journal: Medicinal Chemistry
Volume: 5 Issue: 2 Year: 2009 Page: 165-170
Author(s): Anna Capasso

Reverse Fingerprinting and Mutual Information-Based Activity Labeling and Scoring (MIBALS)

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 4 Year: 2009 Page: 424-439
Author(s): Chris Williams, Suzanne K. Schreyer

Confocal Microscopy Evidence of Prion Protein Fragment hPrP[173-195] Internalization in Rat B104 Neuroblastoma Cell Line

Journal: Protein & Peptide Letters
Volume: 16 Issue: 1 Year: 2009 Page: 1281-1290
Author(s): Emanuela Urso, Raffaele Acierno, Maria Giulia Lionetto, Antonia Rizzello, Andrea Papa, Trifone Schettino, Michele Maffia

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