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Novel Quantitative Structure-Activity Studies of HIV-1 Protease Inhibitors of the Cyclic Urea Type Using Descriptors Derived from Molecular Dynamics and Molecular Orbital Calculations

Journal: Current Computer-Aided Drug Design
Volume: 5 Issue: 1 Year: 2009 Page: 38-55
Author(s): Tatsusada Yoshida, Toshio Fujita, Hiroshi Chuman

Revisiting the Metabolism of Ketoconazole Using Accurate Mass

Journal: Drug Metabolism Letters
Volume: 3 Issue: 3 Year: 2009 Page: 191-198
Author(s): William L. Fitch, Thuy Tran, May Young, Liling Liu, Yuan Chen

Drug Metabolism and Pharmacokinetics in Support of Drug Design

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 1 Year: 2009 Page: 2170-2183
Author(s): Wei Tang, Anthony Y.H. Lu

Cutaneous Metabolism in Transdermal Drug Delivery

Journal: Current Drug Metabolism
Volume: 10 Issue: 3 Year: 2009 Page: 227-235
Author(s): Qian Zhang, Jeffrey E. Grice, Guangji Wang, Michael S. Roberts

Synthesis and Antibacterial Activities of (9S)-3-O-descladinose-6-Omethyl- 3-oxo-12-(Δ 2-pyrazolinyl)-12-dehydroxy-21-demethyl-9- dihydroerythromycin A

Journal: Letters in Organic Chemistry
Volume: 6 Issue: 4 Year: 2009 Page: 306-310
Author(s): Yong-Tao Wang, Lei Hu, Wei-Min Chen, Ai-Xi Hu, Qiu-Ling Song, Dong Guan

Synthesis and Antitumor Evaluation of Thiophene Analogs of Kigelinone

Journal: Letters in Organic Chemistry
Volume: 6 Issue: 4 Year: 2009 Page: 278-281
Author(s): Jaime A. Valderrama, Omar Espinoza, Jaime Rodriguez, Cristina Theoduloz

Foreign Compounds and Intermediary Metabolism: Sulfoxidation Bridges the Divide

Journal: Current Drug Metabolism
Volume: 10 Issue: 3 Year: 2009 Page: 220-226
Author(s): S. C. Mitchell, G. B. Steventon

Importance of Influx and Efflux Systems and Xenobiotic Metabolizing Enzymes in Intratumoral Disposition of Anticancer Agents

Journal: Current Cancer Drug Targets
Volume: 9 Issue: 5 Year: 2009 Page: 652-674
Author(s): B. Rochat

Metabolite Identification and Profiling in Drug Design: Current Practice and Future Directions

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 1 Year: 2009 Page: 2220-2235
Author(s): Zhoupeng Zhang, Mingshe Zhu, Wei Tang

Journal: Current Drug Metabolism
Volume: 10 Issue: 5 Year: 2009 Page: 470-481
Author(s): Jorg Thomas Hartmann, Michael Haap, Hans-Georg Kopp, Hans-Peter Lipp