Search Result "CYP450 system"


The Coordinated Role of CYP450 Enzymes and P-gp in Determining Cancer Resistance to Chemotherapy

Journal: Current Drug Metabolism
Volume: 12 Issue: 8 Year: 2011 Page: 713-721
Author(s): Amalia Azzariti, Letizia Porcelli, Anna Elisa Quatrale, Nicola Silvestris, Angelo Paradiso

Modulation and Absorption of Xenobiotics: The Synergistic Role of CYP450 and P-gp Activities in Cancer and Neurodegenerative Disorders

Journal: Current Drug Metabolism
Volume: 12 Issue: 8 Year: 2011 Page: 702-712
Author(s): Carmela Inglese, Maria Grazia Perrone, Francesco Berardi, Roberto Perrone, Nicola Antonio Colabufo

An Expanded, Unified Substrate Recognition Site Map for Mammalian Cytochrome P450s: Analysis of Molecular Interactions Between 15 Mammalian CYP450 Isoforms and 868 Substrates

Journal: Current Drug Metabolism
Volume: 12 Issue: 7 Year: 2011 Page: 684-700
Author(s): Alexander Zawaira, Lim Yen Ching, Lauren Coulson, Jonathan Blackburn, Yap Chun Wei

A Comparative Study of the CYP450 Inhibition Potential of Marketed Drugs Using Two Fluorescence Based Assay Platforms Routinely Used in the Pharmaceutical Industry

Journal: Drug Metabolism Letters
Volume: 5 Issue: 1 Year: 2011 Page: 30-39
Author(s): Mahmud Kajbaf, Raffaele Longhi, Dino Montanari, Federica Vinco, Monica Rigo, Stefano Fontana, Kevin D. Read

Advances in Human Cytochrome P450 and Personalized Medicine

Journal: Current Drug Metabolism
Volume: 12 Issue: 5 Year: 2011 Page: 436-444
Author(s): Qi Chen, Tao Zhang, Jing-Fang Wang, Dong-Qing Wei

Editorial [Hot Topic: Modulation, Absorption and Delivery of Xenobiotics: The Synergic Role of CYP450 and P-gp Activities (Guest Editor: Nicola Antonio Colabufo)]

Journal: Current Drug Metabolism
Volume: 12 Issue: 8 Year: 2011 Page: 701-701
Author(s): Nicola Antonio Colabufo

Treatment of Central Nervous System Tuberculosis Infections and Neurological Complications of Tuberculosis Treatment

Journal: Current Pharmaceutical Design
Volume: 17 Issue: 2 Year: 2011 Page: 2940-2947
Author(s): J. J. van der Harst, G. J. Luijckx

Discovery and ADMET: Where Are We Now

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 467-481
Author(s): Dennis A. Smith

P-glycoprotein Inhibition: The Past, the Present and the Future

Journal: Current Drug Metabolism
Volume: 12 Issue: 8 Year: 2011 Page: 722-731
Author(s): Richard A.J. Darby, Richard Callaghan, Roisin M. McMahon

Impact of Computational Structure-Based Predictive Toxicology in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 5 Year: 2011 Page: 417-426
Author(s): Chethampadi Gopi Mohan

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