Search Result "CDK2"


Research Article

In Silico Drug Design: Development of New Pyrimidine-based Benzothiazole Derivatives, Selective for CDK2

Journal: Letters in Drug Design & Discovery
Volume: 18 Issue: 0 Year: 2021 Page: 1-15
Author(s): Rania Kasmi,Larbi Elmchichi,Abdellah El Aissouq,Mohammed Bouachrine,Abdelkrim Ouammou

Review Article

Computational Prediction of Binding Affinity for CDK2-ligand Complexes.A Protein Target for Cancer Drug Discovery

Journal: Current Medicinal Chemistry
Volume: 29 Issue: 1 Year: 2022 Page: 2438-2455
Author(s): Martina Veit-Acosta,Walter Filgueira de Azevedo Junior

Research Article

Novel Pyrazolo[3,4-d]pyrimidines as Potential Cytotoxic Agents: Design, Synthesis, Molecular Docking and CDK2 Inhibition

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 19 Issue: 1 Year: 2019 Page: 1368-1381
Author(s): Mai Maher,Asmaa E. Kassab,Ashraf F. Zaher,Zeinab Mahmoud

Research Article

Identification of Novel Cyclin A2 Binding site and Nanomolar Inhibitors of Cyclin A2-CDK2 Complex

Journal: Current Computer-Aided Drug Design
Volume: 17 Issue: 1 Year: 2021 Page: 57-68
Author(s): Stephanie S. Kim,Michele Joana Alves,Patrick Gygli,Jose Otero,Steffen Lindert

Research Article

Synthesis of Some Novel Benzimidazole Derivatives as Anticancer Agent, and Evaluation for CDK2 Inhibition Activity

Journal: Medicinal Chemistry
Volume: 17 Issue: 0 Year: 2021 Page: 1-11
Author(s): Rania Helmy Abd El-Hameed,Samar Said Fatahala,Amira Ibrahim Sayed

Solution Phase Synthesis of a 3,5,7-Substituted Indolin-2-one Library as Potential CDK2 Inhibitor Isosteres

Journal: Letters in Drug Design & Discovery
Volume: 5 Issue: 1 Year: 2008 Page: 43-47
Author(s): Dmytro O. Tymoshenko, Brian T. Gregg, Matthew J. Hirsch, Jennifer L. Butcher

Editorial free to download

Protein-Ligand Interactions: High-Resolution Structures of CDK2

Journal: Current Drug Targets
Volume: 23 Issue: 5 Year: 2022 Page: 438-440
Author(s): Walter Filgueira de Azevedo Jr.

Research Article

3D-QSAR Studies on 4,5-Dihydro-1H-pyrazolo [4,3-h] Quinazolines as Plk-1, CDK2/A and Aur-A Serine/Threonine Kinase Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 4 Year: 2020 Page: 386-393
Author(s): Bhoomendra A. Bhongade,Nikhil D. Amnerkar,Andanappa K. Gadad

Review Article

Cyclin-Dependent Kinase 2 in Cellular Senescence and Cancer. A Structural and Functional Review

Journal: Current Drug Targets
Volume: 20 Issue: 7 Year: 2019 Page: 716-726
Author(s): Priscylla Andrade Volkart,Gabriela Bitencourt-Ferreira,André Arigony Souto,Walter Filgueira de Azevedo

Research Article

Design, Synthesis and Biological Evaluation of Pyrido[2,3-d] Pyrimidine Derivatives as Potential Anticancer Agents

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 1 Year: 2018 Page: 1240-1251
Author(s): Jamelah S. Al-Otaibi,Diaa A. Ibrahim,Tarek M. EL Gogary

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