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New Targets for Therapy in Polyglutamine (polyQ) Expansion Diseases

Journal: Current Drug Therapy
Volume: 3 Issue: 3 Year: 2008 Page: 177-189
Author(s): Lorena Perrone, Mariarosa A.B. Melone

Molecular Genetics and Biomarkers of Polyglutamine Diseases

Journal: Current Molecular Medicine
Volume: 8 Issue: 3 Year: 2008 Page: 221-234
Author(s): Masahisa Katsuno, Haruhiko Banno, Keisuke Suzuki, Yu Takeuchi, Motoshi Kawashima, Fumiaki Tanaka, Hiroaki Adachi, Gen Sobue

A Critical Evaluation of Adenosine A2A Receptors as Potentially “Druggable” Targets in Huntingtons Disease

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 1 Year: 2008 Page: 1500-1511
Author(s): Patrizia Popoli, David Blum, Maria Rosaria Domenici, Sylvie Burnouf, Yijuang Chern

Neuropsychiatric and Cognitive Symptoms in Spinocerebellar Ataxia: Relationship to Neuropathological Differences

Journal: Current Psychiatry Reviews
Volume: 4 Issue: 3 Year: 2008 Page: 157-161
Author(s): Aaron M. McMurtray, Erin Saito, Susan Perlman

Conformational Changes and Aggregation of Expanded Polyglutamine Proteins as Therapeutic Targets of the Polyglutamine Diseases: Exposed β-Sheet Hypothesis

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 3 Year: 2008 Page: 3267-3279
Author(s): Yoshitaka Nagai, H. Akiko Popiel

Molecular Effects of the CTG Repeats in Mutant Dystrophia Myotonica Protein Kinase Gene

Journal: Current Genomics
Volume: 9 Issue: 8 Year: 2008 Page: 509-516
Author(s): Beatriz Llamusi, Ruben Artero

Histone Deacetylase Inhibitors: Therapeutic Agents and Research Tools for Deciphering Motor Neuron Diseases

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2008 Page: 1263-1273
Author(s): A. Echaniz-Laguna, O. Bousiges, J.-P. Loeffler, A.-L. Boutillier

Congeners of the Enediyne Neocarzinostatin Chromophore: Designed Agents for bulged Nucleic Acid Targets

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 6 Year: 2008 Page: 436-447
Author(s): Graham B. Jones, Yiqing Lin, Dong Ma, Ziwei Xiao, Geum-Sook Hwang, Lizzy Kappen, Irving H. Goldberg

Applications of Lentiviral Vectors for Biology and Gene Therapy of Neurological Disorders

Journal: Current Gene Therapy
Volume: 8 Issue: 6 Year: 2008 Page: 461-473
Author(s): Cecilia Lundberg, Tomas Bjorklund, Thomas Carlsson, Johan Jakobsson, Philippe Hantraye, Nicole Deglon, Deniz Kirik

Contribution of Recent Transgenic Models and Transcriptional Profiling Studies to Our Understanding of the Mechanisms by which Androgens Control Spermatogenesis

Journal: Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 2-13
Author(s): G. Verhoeven, E. Denolet, J. V. Swinnen, A. Willems, F. Claessens, P. T.K. Saunders, R. M. Sharpe, K. De Gendt

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