Search Result "ATP-binding site"


Mitoxantrone Targets the ATP-binding Site of FAK, Binds the FAK Kinase Domain and Decreases FAK, Pyk-2, c-Src, and IGF-1R In Vitro Kinase Activities

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13 Issue: 4 Year: 2013 Page: 546-554
Author(s): Vita M. Golubovskaya, Baotran Ho, Min Zheng, Andrew Magis, David Ostrov, William G. Cance

The Target of Regulating The ATP-binding Cassette A1 Protein (ABCA1): Promoting ABCA1-Mediated Cholesterol Efflux in Different Cells

Journal: Current Pharmaceutical Biotechnology
Volume: 14 Issue: 6 Year: 2013 Page: 623-631
Author(s): Can-Xia Huang,Yu-Ling Zhang

Recent Advances in the Development of Catalytic Inhibitors of Human DNA Topoisomerase IIα As Novel Anticancer Agents

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 5 Year: 2013 Page: 694-709
Author(s): B. Pogorel cnik, A. Perdih, T. Solmajer

ATP Synthase: A Molecular Therapeutic Drug Target for Antimicrobial and Antitumor Peptides

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2013 Page: 1956-1973
Author(s): Zulfiqar Ahmad, Florence Okafor, Sofiya Azim, Thomas F. Laughlin

Allosteric Inhibitors of Bcr-Abl: Towards Novel Myristate-Pocket Binders

Journal: Current Pharmaceutical Biotechnology
Volume: 14 Issue: 5 Year: 2013 Page: 477-487
Author(s): Marco Radi,Silvia Schenone,Maurizio Botta

Target Sites for the Design of Anti-trypanosomatid Drugs Based on the Structure of Dihydroorotate Dehydrogenase

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 1 Year: 2013 Page: 2615-2627
Author(s): Matheus Pinto Pinheiro, Flavio da Silva Emery, M. Cristina Nonato

Nanoparticle- and Liposome-carried Drugs: New Strategies for Active Targeting and Drug Delivery Across Blood-brain Barrier

Journal: Current Drug Metabolism
Volume: 14 Issue: 6 Year: 2013 Page: 625-640
Author(s): Martha Leonor Pinzon-Daza, Ivana Campia, Joanna Kopecka, Ruth Garzon, Dario Ghigo, Chiara Rigant

In Silico Study of Desmosdumotin as an Anticancer Agent: Homology Modeling, Docking and Molecular Dynamics Simulation Approach

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13 Issue: 10 Year: 2013 Page: 1636-1644
Author(s): Changdev G. Gadhe,Gugan Kothandan,Seung Joo Cho

Anticancer Therapeutic Strategies Based on CDK Inhibitors

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 3 Year: 2013 Page: 5327-5332
Author(s): Luca Esposito, Paola Indovina, Flora Magnotti, Daniele Conti, Antonio Giordano

Rational Approaches Towards Lead Optimization of Kinase Inhibitors: The Issue of Specificity

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 26 Year: 2013 Page: 4714-4738
Author(s): Preethi Badrinarayan,G. Narahari Sastry

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