Search Result "ATP-binding pocket"


Allosteric Inhibitors of Bcr-Abl: Towards Novel Myristate-Pocket Binders

Journal: Current Pharmaceutical Biotechnology
Volume: 14 Issue: 5 Year: 2013 Page: 477-487
Author(s): Marco Radi,Silvia Schenone,Maurizio Botta

Recent Advances in the Development of Catalytic Inhibitors of Human DNA Topoisomerase IIα As Novel Anticancer Agents

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 5 Year: 2013 Page: 694-709
Author(s): B. Pogorel cnik, A. Perdih, T. Solmajer

Synthesis, p38 Kinase Inhibitory and Anti-inflammatory Activity of New Substituted Benzimidazole Derivatives

Journal: Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2013 Page: 91-99
Author(s): Ravindra G. Kulkarnia, Stefan A. Laufer, Chandrashekhar V. M, Achaiah Garlapati

ATP Synthase: A Molecular Therapeutic Drug Target for Antimicrobial and Antitumor Peptides

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2013 Page: 1956-1973
Author(s): Zulfiqar Ahmad, Florence Okafor, Sofiya Azim, Thomas F. Laughlin

PfRIO-2 Kinase is a Potential Therapeutic Target of Antimalarial Protein Kinase Inhibitors

Journal: Current Drug Discovery Technologies
Volume: 10 Issue: 1 Year: 2013 Page: 85-91
Author(s): Swagata Nag, KMN Prasad, Ananya Bhowmick, Rohitas Deshmukh, Vishal Trivedi

Anticancer Therapeutic Strategies Based on CDK Inhibitors

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 3 Year: 2013 Page: 5327-5332
Author(s): Luca Esposito, Paola Indovina, Flora Magnotti, Daniele Conti, Antonio Giordano

Rational Approaches Towards Lead Optimization of Kinase Inhibitors: The Issue of Specificity

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 26 Year: 2013 Page: 4714-4738
Author(s): Preethi Badrinarayan,G. Narahari Sastry

In Silico Study of Desmosdumotin as an Anticancer Agent: Homology Modeling, Docking and Molecular Dynamics Simulation Approach

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13 Issue: 10 Year: 2013 Page: 1636-1644
Author(s): Changdev G. Gadhe,Gugan Kothandan,Seung Joo Cho

Potential Application of Network Descriptions for Understanding Conformational Changes and Protonation States of ABC Transporters

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 2 Year: 2013 Page: 4155-4172
Author(s): Tamas Hegedus, Gergely Gyimesi, Merse E. Gaspar, Kristof Z. Szalay, Rajeev Gangal, Peter Csermely

Recent Developments of p38α MAP Kinase Inhibitors as Antiinflammatory Agents Based on the Imidazole Scaffolds

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2013 Page: 1997-2016
Author(s): Ting-Ting Kong, Cheng-Mei Zhang, Zhao-Peng Liu

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