Search Result "ATP-binding pocket"


New Directions in Targeting Protein Kinases: Focusing Upon True Allosteric and Bivalent Inhibitors

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 20 Year: 2012 Page: 2936-2945
Author(s): Vandana Lamba,Indraneel Ghosh

Role of Hsp70 in Cancer Growth and Survival

Journal: Protein & Peptide Letters
Volume: 19 Issue: 6 Year: 2012 Page: 616-624
Author(s): Marcus P.D. Hatfield,Sandor Lovas

Synthesis, Docking and Biological Evaluation of Some Novel 5-bromo-2- (5-aryl-1,3,4-thiadiazol-2-yl)isoindoline-1,3-dione Derivatives Targeting ATP-binding Site of Topoisomerase II

Journal: Letters in Drug Design & Discovery
Volume: 9 Issue: 7 Year: 2012 Page: 668-675
Author(s): Ankur Gupta,Priya Singh,Bhagyashree Kamble,Aditi Kulkarni,Moola Joghee Nanjan Chandrasekar

Polo-Like Kinases Inhibitors

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2012 Page: 3937-3948
Author(s): L. Garuti, M. Roberti, G. Bottegoni

Exploiting Substrate Recognition for Selective Inhibition of Protein Kinases

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 20 Year: 2012 Page: 2914-2920
Author(s): Avital Licht-Murava,Hagit Eldar-Finkelman

Computational Insights for the Discovery of Non-ATP Competitive Inhibitors of MAP Kinases

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 9 Year: 2012 Page: 1173-1185
Author(s): Michael J. Schnieders, Tamer S. Kaoud, Chunli Yan, Kevin N. Dalby, Pengyu Ren

Small Molecule Kinase Inhibitors as Anti-Cancer Therapeutics

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 12 Issue: 5 Year: 2012 Page: 399-411
Author(s): O. Chahrour,D. Cairns,Z. Omran

P2X1 and P2X2 Receptors in the Central Nervous System as Possible Drug Targets

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 11 Issue: 6 Year: 2012 Page: 675-686
Author(s): Ralf Hausmann,Gunther Schmalzing

Cis-enone Resorcylic Acid Lactones (RALs) as Irreversible Protein Kinase Inhibitors

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 9 Year: 2012 Page: 1186-1198
Author(s): Linyi Wei, Jiuhong Wu, Guanqun Li, Ning Shi

Docking Prediction for Luteolin Inhibiting TNF-α and NF-κB Pathway

Journal: Letters in Drug Design & Discovery
Volume: 9 Issue: 2 Year: 2012 Page: 169-176
Author(s): Jui-Chiang Sun, S. T. Wua, Kuei-Jen Lee, Yu-Ming Sun

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