Search Result "APP."


BRI2 Interacts with BACE1 and Regulates Its Cellular Levels by Promoting its Degradation and Reducing Its mRNA Levels

Journal: Current Alzheimer Research
Volume: 10 Issue: 5 Year: 2013 Page: 532-541
Author(s): Maria Tsachaki, Angeliki Fotinopoulou, Nefeli Slavi, Vasiliki Zarkou, Jorge Ghiso, Spiros Efthimiopoulos

Pharmacological Activation of LXRs Decreases Amyloid-β Levels in Niemann-Pick Type C Model Cells

Journal: Current Pharmaceutical Biotechnology
Volume: 14 Issue: 6 Year: 2013 Page: 582-593
Author(s): Jasminka Stefulj,Maja Peric,Martina Malnar,Marko Kosicek,Cornelia Schweinzer,Jelena Zivkovic,Monika Scholler,Ute Panzenboeck,Silva Hecimovic

Reduction of β-Amyloid Accumulation by Reticulon 3 in Transgenic Mice

Journal: Current Alzheimer Research
Volume: 10 Issue: 2 Year: 2013 Page: 135-142
Author(s): Wataru Araki,Akiko Oda,Kazumi Motoki,Kotaro Hattori,Masayuki Itoh,Shigeki Yuasa,Yoshihiro Konishi,Ryong-Woon Shin,Akira Tamaoka,Koichi Ogino

Distinct Roles of sAPP-α and sAPP-β in Regulating U251 Cell Differentiation

Journal: Current Alzheimer Research
Volume: 10 Issue: 7 Year: 2013 Page: 706-713
Author(s): Junfeng Jiang,Yue Wang,Lei Hou,Lixing Fan,Qiaoling Wang,Zhenyu Xu,Qing Sun,Houqi Liu

Evidence that Enzyme Processivity Mediates Differential Aβ Production by PS1 and PS2

Journal: Current Alzheimer Research
Volume: 10 Issue: 1 Year: 2013 Page: 4-10
Author(s): Sean A. Pintchovski,Dale B. Schenk,Guriqbal S. Basi

Efficacy and Toxicity of Clioquinol Treatment and A-beta42 Inoculation in the APP/PSI Mouse Model of Alzheimer's Disease

Journal: Current Alzheimer Research
Volume: 10 Issue: 5 Year: 2013 Page: 494-506
Author(s): Yi-Hong Zhang, James Raymick, Sumit Sarkar, Debomoy K. Lahiri, Balmiki Ray, David Holtzman, Melanie Dumas, Larry C. Schmued

Denervation of the Olfactory Bulb Leads to Decreased Aβ Plaque Load in a Transgenic Mouse Model of Alzheimer’ s Disease

Journal: Current Alzheimer Research
Volume: 10 Issue: 7 Year: 2013 Page: 688-696
Author(s): OIivier Bibari,Siak Lee,Tracey C. Dickson,Stan Mitew,James C. Vickers,Meng I. Chuah

Synthesis of the Alzheimer Drug Posiphen into its Primary Metabolic Products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their Inhibition of Amyloid Precursor Protein, α -Synuclein Synthesis, Interleukin-1β Release, and Cholinergic Action.

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 12 Issue: 2 Year: 2013 Page: 117-128
Author(s): Qian-sheng Yu, Marcella Reale, Mohammad A. Kamal, Harold W. Holloway, Weiming Luo, Kumar Sambamurti, Balmiki Ray, Debomoy K. Lahiri, Jack T. Rogers, Nigel H. Greig

Autophagy Enhancer Carbamazepine Alleviates Memory Deficits and Cerebral Amyloid-β Pathology in a Mouse Model of Alzheimer's Disease

Journal: Current Alzheimer Research
Volume: 10 Issue: 4 Year: 2013 Page: 433-441
Author(s): Lixi Li, Sufang Zhang, Xin Zhang, Ting Li, Yu Tang, Hui Liu, Wendi Yang, Weidong Le

Alzheimer's Disease and Diabetes: New Insights and Unifying Therapies

Journal: Current Diabetes Reviews
Volume: 9 Issue: 3 Year: 2013 Page: 218-227
Author(s): Arianna Vignini, Alessia Giulietti, Laura Nanetti, Francesca Raffaelli, Lucia Giusti, Laura Mazzanti, Leandro Provinciali

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