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Fragment-Based Discovery of Inhibitors of Protein Kinase B

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1705-1717
Author(s): Thomas G. Davies, Steven J. Woodhead, Ian Collins

Targeted Inhibition of AKT in Pancreatic Cancer

Journal: Current Cancer Therapy Reviews
Volume: 5 Issue: 4 Year: 2009 Page: 288-295
Author(s): Tawnya L. Bowles, Colin Parsons, Diego J. Muilenburg, Richard J. Bold

Regulation and Importance of the PI3K/Akt/mTOR Signaling Pathway in Hematologic Malignancies

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 9 Issue: 9 Year: 2009 Page: 1024-1038
Author(s): Kiyotaka Kawauchi, Toshie Ogasawara, Masako Yasuyama, Kuniaki Otsuka, Osamu Yamada

The PI3K/Akt Pathway as a Target in the Treatment of Hematologic Malignancies

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 9 Issue: 5 Year: 2009 Page: 550-559
Author(s): Kiyotaka Kawauchi, Toshie Ogasawara, Masako Yasuyama, Kuniaki Otsuka, Osamu Yamada

Targeted Small-Molecule Inhibitors of Protein Kinase B as Anticancer Agents

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 32-50
Author(s): Ian Collins

Role of PI3K/AKT, cPLA2 and ERK1/2 Signaling Pathways in Insulin Regulation of Vascular Smooth Muscle Cells Proliferation

Journal: Cardiovascular & Hematological Disorders-Drug Targets
Volume: 9 Issue: 3 Year: 2009 Page: 172-180
Author(s): Esma R. Isenovic, Mamdouh H. Kedees, Snezana Tepavcevic, Tijana Milosavljevic, Goran Koricanac, Andreja Trpkovic, Pierre Marche

PI-3 Kinase-PTEN Signaling Node: An Intercept Point for the Control of Angiogenesis

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 4 Year: 2009 Page: 380-388
Author(s): R. C. Castellino, C. R. Muh, D. L. Durden

Brain-Derived Neurotrophic Factor (BDNF) has Proliferative Effects on Neural Stem Cells through the Truncated TRK-B Receptor, MAP Kinase, AKT, and STAT-3 Signaling Pathways

Journal: Current Neurovascular Research
Volume: 6 Issue: 1 Year: 2009 Page: 42-53
Author(s): Omedul Islam, Tze X. Loo, Klaus Heese

Gadd45 Proteins as Critical Signal Transducers Linking NF-κB to MAPK Cascades

Journal: Current Cancer Drug Targets
Volume: 9 Issue: 8 Year: 2009 Page: 915-930
Author(s): Z. Yang, L. Song, C. Huang

The AKT Axis as a Therapeutic Target in Autoimmune Diseases

Journal: Endocrine, Metabolic & Immune Disorders - Drug Targets
Volume: 9 Issue: 2 Year: 2009 Page: 145-150
Author(s): Tianfu Wu, Chandra Mohan

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