Search Result "ADME-Tox"


Research Article

Structure-Based Drug Design, Molecular Dynamics and ADME/Tox to Investigate Protein Kinase Anti-Cancer Agents

Journal: Current Bioactive Compounds
Volume: 13 Issue: 3 Year: 2017 Page: 213-222
Author(s): Evelyn M.L.P. Diniz,João G.C. Poiani,Carlton A. Taft,Carlos H.T.P. da Silva

Research Article

Physicochemical Characterization of Mitragyna speciosa Alkaloid Extract and Mitragynine using In Vitro High Throughput Assays

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 20 Issue: 9 Year: 2017 Page: 796-803
Author(s): Wai Mun Kong,Zamri Chik,Zahurin Mohamed,Mohammed A. Alshawsh

Review Article

Recent Updates on Computer-aided Drug Discovery: Time for a Paradigm Shift

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2017 Page: 3296-3307
Author(s): Talambedu Usha,Dhivya Shanmugarajan,Arvind Kumar Goyal,Chinaga Suresh Kumar,Sushil Kumar Middha

Research Article

An Improved Comparative Docking Approach for Developing Specific Glycogen Phosphorylase Inhibitors Using Pentacyclic Triterpenes

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 14 Year: 2017 Page: 1640-1645
Author(s): V. Badireenath Konkimalla

Research Article

Molecular Modeling and Dynamics Simulation Analysis of KATNAL1 for Identification of Novel Inhibitor of Sperm Maturation

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 20 Issue: 1 Year: 2017 Page: 82-92
Author(s): Kishore Sarma,Shubhadeep Roychoudhury,Sudipta Sankar Bora,Budheswar Dehury,Pratap Parida,Saurav Das,Robin Das,Chandrajit Dohutia,Sangeeta Nath,Bibhas Deb,Mahendra K Modi

Review Article

Protein and Peptide Biopharmaceuticals: An Overview

Journal: Protein & Peptide Letters
Volume: 24 Issue: 2 Year: 2017 Page: 94-101
Author(s): Dominic Agyei,Ishtiaq Ahmed,Zain Akram,Hafiz M. N. Iqbal,Michael K. Danquah

Review Article

Dual-acting of Hybrid Compounds - A New Dawn in the Discovery of Multi-target Drugs: Lead Generation Approaches

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 9 Year: 2017 Page: 1096-1114
Author(s): Azizeh Abdolmaleki,Jahan B. Ghasemi

Research Article

Grid-independent Descriptors (GRIND) Analysis and SAR Guided Molecular Docking Studies to Probe Selectivity Profiles of Inhibitors of Multidrug Resistance Transporters ABCB1 and ABCG2

Journal: Current Cancer Drug Targets
Volume: 17 Issue: 2 Year: 2017 Page: 177-190
Author(s): Talha Shafi,Ishrat Jabeen

Review Article

Computer Aided Drug Design for Multi-Target Drug Design: SAR /QSAR, Molecular Docking and Pharmacophore Methods

Journal: Current Drug Targets
Volume: 18 Issue: 5 Year: 2017 Page: 556-575
Author(s): Azizeh Abdolmaleki,Jahan B. Ghasemi,Fatemeh Ghasemi

Research Article

Novel Ferulic Acid-donepezil Hybrids as Multifunctional Agents for th e Treatment of Alzheimer’s Disease with Butyrylcholinesterase, Amyloid- β, Antioxidant and Neuroprotective Properties

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 8 Year: 2017 Page: 918-929
Author(s): Tianping Li,Wanli Pan,Keren Wang,Wenmin Liu,Qianwen Ma,Zhipei Sang

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