Search Result "ADME properties"


Research Article

Design, Synthesis, Characterization, Molecular Docking, ADME Properties and In Vivo Antipsychotic Activity of Aripiprazole Related Drugs Candidates

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 9 Year: 2017 Page: 1073-1085
Author(s): Selvarasu Sekar,Srinivasan Pazhamalai,Ganesan Ariharasivakumar,Mannathusamy Gopalakrishnan

Review Article

In-silico ADME Studies for New Drug Discovery: From Chemical Compounds to Chinese Herbal Medicines

Journal: Current Drug Metabolism
Volume: 18 Issue: 6 Year: 2017 Page: 535-539
Author(s): Guojun Yan,Xiaobing Wang,Zhou Chen,Xianhui Wu,Jinhuo Pan,Yushen Huang,Gang Wan,Zhaogang Yang

Review Article open access plus

A Systematic Analysis of Physicochemical and ADME Properties of All Small Molecule Kinase Inhibitors Approved by US FDA from January 2001 to October 2015

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 29 Year: 2017 Page: 3159-3184
Author(s): Zhihong O`Brien,Mehran F. Moghaddam

Research Article

Structure-Based Drug Design, Molecular Dynamics and ADME/Tox to Investigate Protein Kinase Anti-Cancer Agents

Journal: Current Bioactive Compounds
Volume: 13 Issue: 3 Year: 2017 Page: 213-222
Author(s): Evelyn M.L.P. Diniz,João G.C. Poiani,Carlton A. Taft,Carlos H.T.P. da Silva

Review Article

ADME and Safety Aspects of Non-cleavable Linkers in Drug Discovery and Development

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2017 Page: 3463-3475
Author(s): M. Walles,A. Connor,D. Hainzl

Research Article

Synthesis, ADME Evaluation, and In Vitro Antimycobacterial Studies of a Novel Series of 2-Thiazolylimino-5-Arylidene-4-Thiazolidinone Derivatives

Journal: Anti-Infective Agents
Volume: 15 Issue: 1 Year: 2017 Page: 38-44
Author(s): Alka Mital,Rohani Prasad Burman,Rajesh Gour,Sarbjit Singh Jhamb,Manjinder Singh Gill

Review Article

ADME Considerations for the Development of Biopharmaceutical Conjugates Using Cleavable Linkers

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2017 Page: 3444-3462
Author(s): L. Nathan Tumey,Sean Han

Research Article

Molecular Docking and Structure Activity Relationship Studies of NSAIDs. What do they Reveal about IC50?

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 8 Year: 2017 Page: 949-958
Author(s): Chrysoula Mikra,Georgios Rossos,Sotirios K. Hadjikakou,Nikolaos Kourkoumelis

Research Article

Molecular Docking and In Silico ADMET Study Reveals Flavonoids as a Potential Inhibitor of Aromatase

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 11 Year: 2017 Page: 1267-1276
Author(s): Umang Shah,Samir Patel,Mehul Patel,Jagat Upadhayay

Research Article

Physicochemical Characterization of Mitragyna speciosa Alkaloid Extract and Mitragynine using In Vitro High Throughput Assays

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 20 Issue: 9 Year: 2017 Page: 796-803
Author(s): Wai Mun Kong,Zamri Chik,Zahurin Mohamed,Mohammed A. Alshawsh

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