Search Result "ras-raf-pathway"


Recent Developments in Anti-Cancer Agents Targeting the Ras/Raf/ MEK/ERK Pathway

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 4 Issue: 1 Year: 2009 Page: 28-35
Author(s): Kwong-Kwok Wong

Targeting Ras-RAF-ERK and its Interactive Pathways as a Novel Therapy for Malignant Gliomas

Journal: Current Cancer Drug Targets
Volume: 10 Issue: 8 Year: 2010 Page: 840-848
Author(s): H.-W. Lo

Research Article

Nalbuphine Suppresses Leukemia Stem Cells and Acts Synergistically with ChemotherapyDrugs via Inhibiting Ras/Raf/Mek/Erk Pathway

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 23 Issue: 8 Year: 2023 Page: 922-928
Author(s):

Initial Design and Synthesis of Conformationally Restricted and Pharmacophore-Based Scaffold Hopping Analogs of a Ras Pathway Modulator and Evaluation of Their MAPK Inhibitory Activities

Journal: Letters in Drug Design & Discovery
Volume: 3 Issue: 1 Year: 2006 Page: 44-48
Author(s): Sukumar Sakamuri, Quin-Zene Chen, Yingchun Lu, Yen-Fang Keng, Vladimir Khazak, Katrin Illgen, Silke Schabbert, Lutz Weber, Sanjay R. Menon

Recent Advances of MEK Inhibitors and Their Clinical Progress

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1364-1378
Author(s): Wang John (Yuan), Wilcoxen M. Keith, Nomoto Kenichi, Wu Sara

Review Article

Mutant B-Raf Kinase Inhibitors as Anticancer Agents

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 16 Issue: 12 Year: 2016 Page: 1558-1575
Author(s): Vivek Asati,Sanjay K. Bharti,Debarshi K. Mahapatra

Rationale for Ras and Raf-kinase as a Target for Cancer Therapeutics

Journal: Current Pharmaceutical Design
Volume: 8 Issue: 2 Year: 2002 Page: 2231-2242
Author(s): Michelle Nottage, Lillian L. Siu

Design and Discovery of Small Molecules Targeting Raf-1 Kinase

Journal: Current Pharmaceutical Design
Volume: 8 Issue: 2 Year: 2002 Page: 2269-2278
Author(s): Timothy B. Lowinger, Bernd Riedl, Jacques Dumas, Roger A. Smith

Sorafenib (BAY 43-9006) in Hepatocellular Carcinoma Patients: From Discovery to Clinical Development

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 7 Year: 2012 Page: 938-944
Author(s): G. Ranieri, G. Gadaleta-Caldarola, V. Goffredo, R. Patruno, A. Mangia, A. Rizzo, R. L. Sciorsci, C. D. Gadaleta

Recent Advances in the Research and Development of B-Raf Inhibitors

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2010 Page: 1618-1634
Author(s): Hui-Fang Li, Yadong Chen, Sha-Sha Rao, Xiu-Mei Chen, Hai-Chun Liu, Ji-Hong Qin, Wei-Fang Tang, Yue-Wang, Xiang Zhou, Tao Lu

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