Search Result "lapatinib"


Lapatinib as a Chemotherapeutic Drug

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 4 Issue: 3 Year: 2009 Page: 216-226
Author(s): Oluwakemi Obajimi

Ras-Induced Resistance to Lapatinib is Overcome by MEK Inhibition

Journal: Current Cancer Drug Targets
Volume: 10 Issue: 2 Year: 2010 Page: 168-175
Author(s): G. Zoppoli, E. Moran, D. Soncini, M. Cea, A. Garuti, I. Rocco, G. Cirmena, V. Grillo, L. Bagnasco, G. Icardi, F. Ansaldi, S. Parodi, F. Patrone, A. Ballestrero, A. Nencioni

In vivo behavior and Safety of Lapatinib-Incorporated Lipid Nanoparticles

Journal: Current Pharmaceutical Biotechnology
Volume: 14 Issue: 12 Year: 2013 Page: 1062-1071
Author(s): Huile Gao,Chen Chen,Zhangjie Xi,Jun Chen,Qizhi Zhang,Shilei Cao,Xinguo Jiang

MEK Inhibition Increases Lapatinib Sensitivity Via Modulation of FOXM1

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2013 Page: 2486-2499
Author(s): S.S. Gayle, R.C. Castellino, M.C. Buss, R. Nahta

Design, Synthesis and Biological Evaluation of Lapatinib Derivatives as HER1/HER2 Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 12 Issue: 7 Year: 2015 Page: 574-584
Author(s): Aifeng Lyu,Lei Fang,Shaohua Gou,Xia Liu

Pharmacologic Inhibition of mTOR Improves Lapatinib Sensitivity in HER2-Overexpressing Breast Cancer Cells with Primary Trastuzumab Resistance

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 12 Issue: 2 Year: 2012 Page: 151-162
Author(s): Sylvia S. Gayle, Samuel L.M. Arnold, Ruth M. ORegan, Rita Nahta

Letter to the Editor

Lapatinib as a Dual Tyrosine Kinase Inhibitor Unexpectedly Activates Akt in MDA-MB-231 Triple-Negative Breast Cancer Cells

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 8 Year: 2020 Page: 1060-1063
Author(s): Parham Jabbarzadeh Kaboli,King-Hwa Ling

Lessons from the Drug Discovery of Lapatinib, a Dual ErbB1/2 Tyrosine Kinase Inhibitor

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 5 Year: 2006 Page: 435-460
Author(s): Karen E. Lackey

Tyrosine Kinase Inhibitors Gefitinib, Lapatinib and Sorafenib Induce Rapid Functional Alterations in Breast Cancer Cells

Journal: Current Cancer Drug Targets
Volume: 10 Issue: 4 Year: 2010 Page: 422-431
Author(s): S. Carloni, F. Fabbri, G. Brigliadori, P. Ulivi, R. Silvestrini, D. Amadori, W. Zoli

Targeted Anti-HER2 Cancer Therapy in Elderly Women Diagnosed with Breast Cancer

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 5 Year: 2014 Page: 639-645
Author(s): M.J. Molina-Garrido, C. Guillen-Ponce, A. Mora-Rufete

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