Search Result "drug clearance"


Review Article

Physiologically-based Pharmacokinetic (PBPK) Modelling of Transporter Mediated Drug Absorption, Clearance and Drug-drug Interactions

Journal: Current Drug Metabolism
Volume: 22 Issue: 7 Year: 2021 Page: 523-531
Author(s): Kunal S. Taskar,Isobel Harada,Ravindra V. Alluri

Predicting Clearance in Humans from In Vitro Data

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 334-339
Author(s): R. Scott Obach

Review Article

Optimization of Protein and Peptide Drugs Based on the Mechanisms of Kidney Clearance

Journal: Protein & Peptide Letters
Volume: 25 Issue: 6 Year: 2018 Page: 514-521
Author(s): Jiaguo Huang,Huizi Wu

Research Article

Utility of Pooled Cryopreserved Human Enterocytes as an In vitro Model for Assessing Intestinal Clearance and Drug-Drug Interactions

Journal: Drug Metabolism Letters
Volume: 12 Issue: 1 Year: 2018 Page: 3-13
Author(s): Susan Wong,Utkarsh Doshi,Peter Vuong,Ning Liu,Suzanne Tay,Hoa Le,Mika Kosaka,Jane R. Kenny,Albert P. Li,Zhengyin Yan

The Relevance of Drug Clearance to Antibiotic Dosing in Critically Ill Patients

Journal: Current Pharmaceutical Biotechnology
Volume: 12 Issue: 1 Year: 2011 Page: 2002-2014
Author(s): Darren M. Roberts

Covariates of Amikacin Clearance in Neonates: The Impact of Postnatal Age on Predictability

Journal: Drug Metabolism Letters
Volume: 2 Issue: 4 Year: 2008 Page: 286-289
Author(s): Karel Allegaert, Isabelle Scheers, Veerle Cossey, Brian J. Anderson

Research Article

Drug Utilization in Critically ill Adults with Augmented Renal Clearance Compared to Normal Renal Clearance: Implications for use of Antimicrobials with Predominant Renal Excretion

Journal: Current Clinical Pharmacology
Volume: 15 Issue: 0 Year: 2020 Page: 1-8
Author(s): Kannan Sridharan,Sheikh Abdul Azeez Pasha,Ali M Qader,Hasan MSN Hasan,Mohamed M ElSeirafi

ARC - Augmented Renal Clearance

Journal: Current Pharmaceutical Biotechnology
Volume: 12 Issue: 1 Year: 2011 Page: 2020-2029
Author(s): Andrew A. Udy, Michael T. Putt, Robert J. Boots, Jeffrey Lipman

Controversies in Allometric Scaling for Predicting Human Drug Clearance: An Historical Problem and Reflections on What Works and What Does Not

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 340-350
Author(s): Huadong Tang, Michael Mayersohn

The Impact of In Vitro Binding on In Vitro - In Vivo Extrapolations, Projections of Metabolic Clearance and Clinical Drug-Drug Interactions

Journal: Current Drug Metabolism
Volume: 7 Issue: 3 Year: 2006 Page: 251-264
Author(s): K. Grime, R. J. Riley

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