Search Result "IC50"


Impact of Impurities on IC50 Values of P450 Inhibitors

Journal: Drug Metabolism Letters
Volume: 5 Issue: 3 Year: 2011 Page: 156-162
Author(s): Zeqi Huang

An Examination of IC50 and IC50-Shift Experiments in Assessing Time-Dependent Inhibition of CYP3A4, CYP2D6 and CYP2C9 in Human Liver Microsomes

Journal: Drug Metabolism Letters
Volume: 2 Issue: 1 Year: 2008 Page: 51-59
Author(s): Loren M. Berry, Zhiyang Zhao

Research Article

QSAR Studies on the IC50 of A Class of Thiazolidinone/Thiazolide Based Hybrids as Antitrypanosomal Agents

Journal: Letters in Drug Design & Discovery
Volume: 18 Issue: 4 Year: 2021 Page: 406-415
Author(s): Bo Yang,Hongzong Si,Honglin Zhai

Research Article

Molecular Docking and Structure Activity Relationship Studies of NSAIDs. What do they Reveal about IC50?

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 8 Year: 2017 Page: 949-958
Author(s): Chrysoula Mikra,Georgios Rossos,Sotirios K. Hadjikakou,Nikolaos Kourkoumelis

Research Article

Studies on the IC50 of Metabolically Stable 1-(3,3-diphenylpropyl)- piperidinyl Amides and Ureas as Human CCR5 Receptor Antagonists Based on QSAR

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 8 Year: 2020 Page: 1036-1046
Author(s): Yutao Zhao,Xiaoqian Liu,Jing Ouyang,Yan Wang,Shanyu Xu,Dongdong Tian,Hongzong Si

Qualitative and Quantitative Assessment of Drug-Drug Interaction Potential in Man, Based on Ki, IC50 and Inhibitor Concentration

Journal: Current Drug Metabolism
Volume: 5 Issue: 2 Year: 2004 Page: 147-156
Author(s): N. Blanchard, L. Richert, P. Coassolo, T. Lave

Research Article

DFT based Computational Methodology of IC50 Prediction

Journal: Current Computer-Aided Drug Design
Volume: 17 Issue: 2 Year: 2021 Page: 244-253
Author(s): Arijit Bag

A Transcellular Assay to Assess the P-gp Inhibition in Early Stage of Drug Development

Journal: Drug Metabolism Letters
Volume: 6 Issue: 4 Year: 2012 Page: 285-291
Author(s): Jan-Shiang Taur, Edgar L. Schuck, Nancy Y. Wong

Perspective

Perspective on the Relationship between GABAA Receptor Activity and theApparent Potency of an Inhibitor

Journal: Current Neuropharmacology
Volume: 20 Issue: 1 Year: 2022 Page: 90-93
Author(s): Allison L. Germann,Spencer R. Pierce,Alex S. Evers,Joe Henry Steinbach,Gustav Akk

Research Article

Inhibition Profiling of Urease and Carbonic Anhydrase II by High- Throughput Screening and Molecular Docking Studies of Structurally Diverse Organic Compounds

Journal: Letters in Drug Design & Discovery
Volume: 18 Issue: 3 Year: 2021 Page: 299-312
Author(s): Majid Ali,Syed Majid Bukhari,Asma Zaidi,Farhan A. Khan,Umer Rashid,Neelum Tahir,Baseerat Rabbani,Umar Farooq

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