Search Result "vla-4 potency"


The Discovery of VLA-4 Antagonists

Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 1 Year: 2004 Page: 1509-1523
Author(s): Jefferson W. Tilley, Li Chen, Achyutharao Sidduri, Nader Fotouhi

The Identification and Optimization of Orally Efficacious, Small Molecule VLA-4 Antagonists

Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 1 Year: 2004 Page: 1473-1484
Author(s): Donna M. Huryn, Andrei W. Konradi, Susan Ashwell, Stephen B. Freedman, Louis J. Lombardo, Michael A. Pleiss, Eugene D. Thorsett, Ted Yednock, Jeffrey D. Kennedy

The Discovery and Potential of N-Sulfonylated Dipeptide VLA-4 Antagonists

Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 1 Year: 2004 Page: 1461-1471
Author(s): William K. Hagmann

Rational Design of Potent and Selective VLA-4 Inhibitors and their Utility in the Treatment of Asthma

Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 1 Year: 2004 Page: 1497-1507
Author(s): Juswinder Singh, Steve Adams, Mary Beth Carter, Hernan Cuervo, Wen-Cherng Lee, Roy R. Lobb, R. Blake Pepinsky, Russell Petter, Daniel Scott

The Discovery of CDP323, a Potent Alpha4 Integrin Antagonist

Journal: Current Immunology Reviews
Volume: 8 Issue: 2 Year: 2012 Page: 135-140
Author(s): Stuart Bailey, Roger Palframan, Gillian Watt, John Porter

Fluorinated Compounds in Medicinal Chemistry: Recent Applications, Synthetic Advances and Matched-Pair Analyses

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 7 Year: 2014 Page: 855-864
Author(s): David Barnes-Seeman, Jeremy Beck, Clayton Springer

Novel Targets and Derived Small Molecule Inhibitors in Multiple Myeloma

Journal: Current Cancer Drug Targets
Volume: 12 Issue: 7 Year: 2012 Page: 797-813
Author(s): Klaus Podar

Transgenic Mouse Strains as Platforms for the Successful Discovery and Development of Human Therapeutic Monoclonal Antibodies

Journal: Current Drug Discovery Technologies
Volume: 11 Issue: 1 Year: 2014 Page: 74-84
Author(s): Larry L. Green

Therapeutic Antibodies in HIV Treatment - Classical Approaches to Novel Advances

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 3 Year: 2010 Page: 3754-3766
Author(s): Irene A. Abela, Lucy Reynell, Alexandra Trkola

Gene Therapy and Biologic Therapy with Interleukin?4

Journal: Current Gene Therapy
Volume: 2 Issue: 4 Year: 2002 Page: 437-450
Author(s): Hideho Okada, Naruo Kuwashima

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