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Search Result "pyrimidine-2-amines"

4-Thiophenoxy-N-(3,4,5-Trialkoxyphenyl)Pyrimidine-2-Amines as Potent and Selective Inhibitors of the T-Cell Tyrosine Kinase p56lck

Journal: Current Medicinal Chemistry
Volume: 11 Issue: 6 Year: 2004 Page: 747-753
Author(s): D. F.C. Moffat, R. A. Allen, S. E. Rapecki, P. D. Davis, J. OConnell, M. C. Hutchings, M. A. King, B. A. Boyce, M. J. Perry

Research Article

Discovery of N-Phenyl-4-(1H-pyrrol-3-yl)pyrimidin-2-amine Derivatives as Potent Mnk2 Inhibitors: Design, Synthesis, SAR Analysis, and Evaluation of in vitro Anti-leukaemic Activity

Journal: Medicinal Chemistry
Volume: 15 Issue: 6 Year: 2019 Page: 600-621
Author(s): Ahmed M. Abdelaziz,Sarah Diab,Saiful Islam,Sunita K. C. Basnet,Benjamin Noll,Peng Li,Laychiluh B. Mekonnen,Jingfeng Lu,Hugo Albrecht,Robert W. Milne,Cobus Gerber,Mingfeng Yu,Shudong Wang

Research Article

Design, Synthesis and Therapeutic Potential of Some 6, 6'-(1,4- phenylene)bis(4-(4-bromophenyl)pyrimidin-2-amine)analogues

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 19 Issue: 7 Year: 2019 Page: 609-621
Author(s): Sanjiv Kumar,Balasubramanian Narasimhan,Siong Meng Lim,Kalavathy Ramasamy,Vasudevan Mani,Syed Adnan Ali Shah

Research Article

Fragment-Based Drug Design, 2D-QSAR and DFT Calculation: Scaffoldsof 1, 2, 4, triazolo [1, 5-a] pyrimidin-7-amines as Potential Inhibitors ofPlasmodium falciparum Dihydroorotate Dehydrogenase

Journal: Letters in Drug Design & Discovery
Volume: 20 Issue: 3 Year: 2023 Page: 317-334
Author(s): Olusola Olalekan Elekofehinti,Prosper Obed Chukwuemeka,Ibukun Mary Folorunso

Synthesis of a 2, 4, 8-Trisubstituted Pyrimidino[5, 4-d]Pyrimidine Library via Sequential SNAr Reactions on Solid-Phase

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 7 Issue: 5 Year: 2004 Page: 413-421
Author(s): M. El-Araby, R. S. Pottorf, M. R. Player

Reactions, Anti-Alzheimer and Anti COX-2 Activities of 6-Pyridin-3-yl-1Hpyrazolo[ 3,4-b]pyridin-3-amines

Journal: Current Organic Chemistry
Volume: 14 Issue: 2 Year: 2010 Page: 2522-2530
Author(s): Fawzy A. Attaby, Azza M. Abdel Fattah, Labeeb M. Shaif, Mohamed M. Elsayed

Research Article

DFT Study On Two Plausible Mechanistic Routes to Pyrazolo[3,4-d]pyrimidine-4- Amines From Pyrazoloformimidate

Journal: Current Organic Chemistry
Volume: 24 Issue: 2 Year: 2020 Page: 216-229
Author(s): Amal Al-Azmi

A Simple Access in One Step to Some New Substituted Pyrazolo- and [1,2,4]triazolo-[1,5-a]pyrimidines

Journal: Letters in Organic Chemistry
Volume: 10 Issue: 2 Year: 2013 Page: 118-120
Author(s): Monaem Balti, Khaireddine Dridi, Mohamed Lotfi El Efrit

Research Article

Synthesis of RNA Bearing C5-polyamine Modified Pyrimidine Nucleosides at the 3´-end by T4 RNA Ligase

Journal: Letters in Organic Chemistry
Volume: 16 Issue: 2 Year: 2019 Page: 122-127
Author(s): Tomokazu Masuda,Shingo Kimura,Mohammad Mehedi Masud,Hiroaki Ozaki

Research Article

New Cyclopenta[4,5]pyrido[3,2:4,5]thieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidines and Cyclopenta[4,5]pyrido[3,2:4,5]thieno[2,3-e][1,2,4]triazolo[1,5-c]pyrimidines: Synthesis and Antimicrobial Activities

Journal: Current Organic Chemistry
Volume: 21 Issue: 1 Year: 2017 Page: 1227-1241
Author(s): Samvel N. Sirakanyan,Domenico Spinelli,Athina Geronikaki,Viktor A. Kartsev,Elmira K. Hakobyan,Henrik A. Panosyan,Hrachya M. Stepanyan,Luca Zuppiroli,Anush A. Hovakimyan

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