Search Result "half-life"


General Review Article

Recent Advances in Half-life Extension Strategies for Therapeutic Peptides and Proteins

Journal: Current Pharmaceutical Design
Volume: 24 Issue: 4 Year: 2018 Page: 4932-4946
Author(s): Huanbo Tan,Wencheng Su,Wenyu Zhang,Pengju Wang,Michael Sattler,Peijian Zou

Review Article

New Directions for Half-Life Extension of Protein Therapeutics: The Rise of Antibody Fc Domains and Fragments

Journal: Current Pharmaceutical Biotechnology
Volume: 17 Issue: 15 Year: 2016 Page: 1348-1352
Author(s): Lili Wang,Tianlei Ying

Research Article

Pegylation and Cell Based Bioassay of Human Interferon-α2b Along Its Docking Studies and Effect on Plasma Half-Life

Journal: Protein & Peptide Letters
Volume: 27 Issue: 3 Year: 2020 Page: 219-224
Author(s): Syeda Kiran Shahzadi,Muhammad Abdul Qadir,Nasir Mahmood,Mehboob Ahmed

Research Article

Higher Anti-angiogenesis Activity, Better Cellular Uptake and Longer Half-life of a Novel Glyco-modified Endostatin by Polysulfated Heparin

Journal: Current Pharmaceutical Biotechnology
Volume: 19 Issue: 1 Year: 2018 Page: 996-1004
Author(s): Feng Sun,Abdul Sami Shaikh,Juan Wang,Hui Gao,Zhifang Yang,Zhendong Wang,Yan Li,Fengshan Wang,Haining Tan

Application of Simple Mathematical Expressions to Relate Half-Lives of Drugs in Mice to Those in Humans

Journal: Drug Metabolism Letters
Volume: 1 Issue: 2 Year: 2007 Page: 127-129
Author(s): Kenneth Bachmann, Jonathan Chupka, Paul Erhardt, Donald White

Plasminogen Activator Inhibitor with Very Long Half-life (VLHL PAI-1) can Reduce Bleeding in PAI-1-deficient Patients

Journal: Cardiovascular & Hematological Disorders-Drug Targets
Volume: 13 Issue: 2 Year: 2013 Page: 144-150
Author(s): Jerzy Jankun, Ewa Skrzypczak-Jankun

In Silico Prediction of Brain Exposure: Drug Free Fraction, Unbound Brain to Plasma Concentration Ratio and Equilibrium Half-Life

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 7 Year: 2013 Page: 813-820
Author(s): Morena Spreafico, Matthew P. Jacobson

Toxicokinetic Interaction Between Quetiapine and Antiretroviral Therapy Following Quetiapine Overdose

Journal: Drug Metabolism Letters
Volume: 4 Issue: 1 Year: 2010 Page: 7-8
Author(s): P. Hantson, V. Di Fazio, P. Wallemacq

Half-Life of Sulfonylureas in HNF1A and HNF4A Human MODY Patients is not Prolonged as Suggested by the Mouse Hnf1a-/- Model

Journal: Current Pharmaceutical Design
Volume: 21 Issue: 3 Year: 2015 Page: 5736-5748
Author(s):

Radioarsenic from a Portable 72Se/72As Generator: A Current Perspective

Journal: Current Radiopharmaceuticals
Volume: 5 Issue: 3 Year: 2012 Page: 264-270
Author(s): B. Ballard,F. M. Nortier,E. R. Birnbaum,K. D. John,D. R. Phillips,M. E. Fassbender

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