Search Result "hERG screening"


A Ligand-Based Virtual Screening Approach to Identify Small Molecules as hERG Channel Activators

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 18 Issue: 3 Year: 2015 Page: 269-280
Author(s): Elisa Giacomini, Rosa Buonfiglio, Matteo Masetti, Yuhong Wang, Gea-Ny Tseng, Marinella Roberti, Maurizio Recanatini

Ligand Structural Aspects of hERG Channel Blockade

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1113-1127
Author(s): Alex M. Aronov

hERG (KCNH2 or Kv11.1) K+ Channels: Screening for Cardiac Arrhythmia Risk

Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 965-970
Author(s): Mark R. Bowlby, Ravi Peri, Howard Zhang, John Dunlop

Recent Developments in Computational Prediction of hERG Blockage

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 1317-1326
Author(s): Sichao Wang, Youyong Li, Lei Xu, Dan Li, Tingjun Hou

Review Article

How to Fluorescently Label the Potassium Channel: A Case in hERG

Journal: Current Medicinal Chemistry
Volume: 27 Issue: 1 Year: 2020 Page: 3046-3054
Author(s): Xiaomeng Zhang,Beilei Wang,Zhenzhen Liu,Yubin Zhou,Lupei Du

In Silico hERG Modeling: Challenges and Progress

Journal: Current Computer-Aided Drug Design
Volume: 5 Issue: 2 Year: 2009 Page: 106-121
Author(s): David J. Diller

The hERG Channel and Risk of Drug-Acquired Cardiac Arrhythmia: An Overview

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1102-1112
Author(s): Armando A. Lagrutta, Elena S. Trepakova, Joseph J. Salata

Lead Optimization of Melanin Concentrating Hormone Receptor 1 Antagonists with low hERG Channel Activity

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1152-1157
Author(s): Andrew S. Judd, Andrew J. Souers, Philip R. Kym

Overcoming hERG Affinity in the Discovery of Maraviroc; A CCR5 Antagonist for the Treatment of HIV

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1140-1151
Author(s): David A. Price, Duncan Armour, Marcel de Groot, Derek Leishman, Carolyn Napier, Manos Perros, Blanda L. Stammen, Anthony Wood

In Silico Predictions of hERG Channel Blockers in Drug Discovery: From Ligand-Based and Target-Based Approaches to Systems Chemical Biology

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 5 Year: 2011 Page: 375-387
Author(s): Olivier Taboureau, Flemming Steen Jorgensen

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