Search Result "geranylgeranyltransferase"


Research Article

Protein Geranylgeranyltransferase Type 1 as a Target in Cancer

Journal: Current Cancer Drug Targets
Volume: 16 Issue: 7 Year: 2016 Page: 563-571
Author(s): Nisar Ullah, Muhammad Mansha, Patrick J. Casey

Theoretical Studies on Binding and Specificity Mechanisms of Farnesyltransferase (FTase) and Geranylgeranyltransferase Type-I (GGTase-I) Inhibitors by Molecular Modeling

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 6 Year: 2014 Page: 509-519
Author(s): Shirou Zhou

Inhibitors of Farnesyltransferase and Geranylgeranyltransferase-I for Antitumor Therapy: Substrate-Based Design, Conformational Constraint and Biological Activity

Journal: Current Topics in Medicinal Chemistry
Volume: 3 Issue: 1 Year: 2003 Page: 1075-1093
Author(s): Christopher J. Dinsmore, Ian M. Bell

Inhibitors of Protein Prenylation: An Overview

Journal: Current Enzyme Inhibition
Volume: 1 Issue: 2 Year: 2005 Page: 183-206
Author(s): Saswati Banerjee, Paul McGeady

Review Article

Inhibiting the “Undruggable” RAS/Farnesyltransferase (FTase) CancerTarget by Manumycin-related Natural Products

Journal: Current Medicinal Chemistry
Volume: 29 Issue: 2 Year: 2022 Page: 189-211
Author(s): Leandro Rocha Silva,Edeildo Ferreira da Silva-Júnior

Exploring Structure-Activity Relationships of Tricyclic Farnesyltransferase Inhibitors Using ECLiPS® Libraries

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 7 Year: 2006 Page: 545-558
Author(s): Laura L. Rokosz, Chia-Yu Huang, John C. Reader, Tara M. Stauffer, Eileen C. Southwick, Ge Li, Daniel Chelsky, John J. Baldwin

Inhibitors of Protein Farnesyltransferase as Novel Anticancer Agents

Journal: Current Topics in Medicinal Chemistry
Volume: 2 Issue: 3 Year: 2002 Page: 303-323
Author(s): Junko Ohkanda, David B. Knowles, Michelle A. Blaskovich, Said M. Sebti, Andrew D. Hamilton

Rho GTPases: Promising Cellular Targets for Novel Anticancer Drugs

Journal: Current Cancer Drug Targets
Volume: 6 Issue: 1 Year: 2006 Page: 1-14
Author(s): Gerhard Fritz, Bernd Kaina

Farnesyltransferase Inhibitors: A Detailed Chemical View on an Elusive Biological Problem

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2008 Page: 1478-1492
Author(s): Sergio F. Sousa, Pedro A. Fernandes, Maria Joao Ramos

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