Search Result "channel activation and blockade"


Insights into the Molecular Mechanism of hERG1 Channel Activation and Blockade by Drugs

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2010 Page: 3514-3532
Author(s): S. Durdagi, J. Subbotina, J. Lees-Miller, J. Guo, H. J. Duff, S. Y. Noskov

Mechanistic View of Renal Protective Action of Calcium Channel Blockade

Journal: Current Hypertension Reviews
Volume: 9 Issue: 3 Year: 2013 Page: 187-192
Author(s): Naoki Sugano, Koichi Hayashi, Tatsuo Hosoya, Takashi Yokoo

Ligand Structural Aspects of hERG Channel Blockade

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1113-1127
Author(s): Alex M. Aronov

A Quantitative Structure-Activity Relationship Study on Some Series of Potassium Channel Blockers

Journal: Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2009 Page: 87-92
Author(s): V. S.A. Kumar Satuluri, Jyostna Seelam, S. P. Gupta

Inhibition of G Protein-Activated Inwardly Rectifying K+ Channels by Phencyclidine

Journal: Current Neuropharmacology
Volume: 9 Issue: 1 Year: 2011 Page: 244-246
Author(s): Toru Kobayashi, Daisuke Nishizawa, Kazutaka Ikeda

New Generation Calcium Channel Blockers in Hypertensive Treatment

Journal: Current Hypertension Reviews
Volume: 2 Issue: 2 Year: 2006 Page: 103-111
Author(s): Yuri Ozawa, Koichi Hayashi, Hiroyuki Kobori

Pharmacological Roles of the Large-Conductance Calcium-Activated Potassium Channel

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 1025-1030
Author(s): Sheng-Nan Wu, Adonis Z Wu, Ming-Wei Lin

Small Conductance Ca2+-Activated K+ Channels as Targets of CNS Drug Development

Journal: Current Drug Targets - CNS & Neurological Disorders
Volume: 3 Issue: 3 Year: 2004 Page: 161-167
Author(s): Thomas Blank, Ingrid Nijholt, Min-Jeong Kye, Joachim Spiess

Bis-Quinolinium Cyclophanes: Highly Potent and Selective Non-Peptidic Blockers of the Apamin-Sensitive Ca2+-Activated K+ Channel

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2008 Page: 1305-1315
Author(s): Ana Conejo-Garcia, Joaquin M. Campos

Physiological and Pharmacological Insights into the Role of Ionic Channels in Cardiac Pacemaker Activity

Journal: Cardiovascular & Hematological Disorders-Drug Targets
Volume: 6 Issue: 3 Year: 2006 Page: 169-190
Author(s): B. Couette, L. Marger, J. Nargeot, M. E. Mangoni

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