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Comparison of Cytochrome P450 2D6 and Variants in Terms of Drug Oxidation Rates and Substrate Inhibition

Journal: Current Drug Metabolism
Volume: 12 Issue: 5 Year: 2011 Page: 412-435
Author(s): Toshiro Niwa, Norie Murayama, Hiroshi Yamazaki

Challenges in Oral Delivery: Role of P-gp Efflux Pump

Journal: Current Drug Therapy
Volume: 9 Issue: 1 Year: 2014 Page: 47-55
Author(s): Karan Mittal,Rajashree C. Mashru,Arti R. Thakkar

Pharmacophore, QSAR, and Binding Mode Studies of Substrates of Human Cytochrome P450 2D6 (CYP2D6) Using Molecular Docking and Virtual Mutations and an Application to Chinese Herbal Medicine Screening

Journal: Current Pharmaceutical Biotechnology
Volume: 13 Issue: 9 Year: 2012 Page: 1640-1704
Author(s): Sui-Lin Mo,Wei-Feng Liu,Chun-Guang Li,Zhi-Wei Zhou,Hai-Bin Luo,Helen Chew,Jun Liang,Shu-Feng Zhou

Utility of Mdr1-Gene Deficient Mice in Assessing the Impact of P-glycoprotein on Pharmacokinetics and Pharmacodynamics in Drug Discovery and Development

Journal: Current Drug Metabolism
Volume: 4 Issue: 4 Year: 2003 Page: 272-291
Author(s): Cuiping Chen, Xingrong Liu, Bill J. Smith

PET Imaging of Beta-Adrenoceptors in Human Brain: A Realistic Goal or a Mirage?

Journal: Current Pharmaceutical Design
Volume: 10 Issue: 1 Year: 2004 Page: 1519-1536
Author(s): Aren van Waarde, Willem Vaalburg, Petra Doze, Fokko J. Bosker, Philip H. Elsinga

Journal: Current Alzheimer Research
Volume: 5 Issue: 4 Year: 2008 Page: 396-405
Author(s): Jens Pahnke, Olaf Wolkenhauer, Markus Krohn, Lary C. Walker

Pharmacogenetics of Drug Transporters and Its Impact on the Pharmacotherapy

Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 1 Year: 2004 Page: 1383-1396
Author(s): Toshiyuki Sakaeda, Tsutomu Nakamura, Katsuhiko Okumura

PET Studies on P-Glycoprotein Function in the Blood-Brain Barrier: How it Affects Uptake and Binding of Drugs within the CNS

Journal: Current Pharmaceutical Design
Volume: 10 Issue: 1 Year: 2004 Page: 1493-1503
Author(s): Philip H. Elsinga, N. Harry Hendrikse, Joost Bart, Willem Vaalburg, Aren van Waarde

An Update on Overcoming MDR1-Mediated Multidrug Resistance in Cancer Chemotherapy

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 3 Year: 2006 Page: 273-286
Author(s): Kohji Takara, Toshiyuki Sakaeda, Katsuhiko Okumura

Pharmacogenetic Aspects of Therapy with Cholinesterase Inhibitors: The Role of CYP2D6 in Alzheimers Disease Pharmacogenetics

Journal: Current Alzheimer Research
Volume: 4 Issue: 4 Year: 2007 Page: 479-500
Author(s): Ramon Cacabelos, Ruth Llovo, Carmen Fraile, Lucia Fernandez-Novoa