Search Result "PolyQ"


New Targets for Therapy in Polyglutamine (polyQ) Expansion Diseases

Journal: Current Drug Therapy
Volume: 3 Issue: 3 Year: 2008 Page: 177-189
Author(s): Lorena Perrone, Mariarosa A.B. Melone

Transcriptional Dysregulation: A Therapeutic Target for Polyglutamine Diseases

Journal: Current Medicinal Chemistry - Central Nervous System Agents
Volume: 5 Issue: 2 Year: 2005 Page: 119-127
Author(s): Jonathan Cornett, Meyer Friedman, Shi-Hua Li, Xiao-Jiang Li

Expanding our Understanding of Polyglutamine Disease Through Transgenic Mice

Journal: Current Genomics
Volume: 2 Issue: 1 Year: 2001 Page: 27-39
Author(s): Jennifer D. Davidson, Harry T. Orr

Therapeutic Prospects for the Prevention of Neurodegeneration in Huntingtons Disease and the Polyglutamine Repeat Disorders

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 99-106
Author(s): Yoko Kimura, Wyan-Ching Mimi Lee, J. Troy Littleton

Therapeutic Approaches to Polyglutamine Diseases: Combating Protein Misfolding and Aggregation

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 2 Year: 2006 Page: 2543-2555
Author(s): Martin Herbst, Erich E. Wanker

Conformational Diseases: Structural Studies of Aggregation of Polyglutamine Proteins

Journal: Current Computer-Aided Drug Design
Volume: 7 Issue: 1 Year: 2011 Page: 23-43
Author(s): Elena Papaleo, Gaetano Invernizzi

Towards the Treatment of Polyglutamine Diseases: The Modulatory Role of Protein Context

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 2 Year: 2010 Page: 3058-3068
Author(s): A. L. Robertson, S. P. Bottomley

Polyglutamine and Neurodegeneration: Structural Aspects

Journal: Protein & Peptide Letters
Volume: 11 Issue: 3 Year: 2004 Page: 239-248
Author(s): Laura Masino

Conformational Changes and Aggregation of Expanded Polyglutamine Proteins as Therapeutic Targets of the Polyglutamine Diseases: Exposed β-Sheet Hypothesis

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 3 Year: 2008 Page: 3267-3279
Author(s): Yoshitaka Nagai, H. Akiko Popiel

Novel Lactulose and Melibiose Targeting Autophagy to Reduce PolyQ Aggregation in Cell Models of Spinocerebellar Ataxia 3

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 15 Issue: 3 Year: 2016 Page: 351-359
Author(s): Chih-Hsin Lin, Yih-Ru Wu, Jinn-Moon Yang, Wan-Ling Chen, Chih-Ying Chao, I-Cheng Chen, Te-Hsien Lin, Yi-Ci Wu, Kai-Cheng Hsu, Chiung-Mei Chen, Guan-Chiun Lee, Hsiu-Mei Hsieh-Li, Chi-Mei Lee, Guey-Jen Lee-Chen

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