Search Result "PfDXR"


The Druggable Antimalarial Target PfDXR: Overproduction Strategies and Kinetic Characterization

Journal: Protein & Peptide Letters
Volume: 20 Issue: 2 Year: 2013 Page: 115-124
Author(s): Jessica L. Goble,Hailey Johnson,Jaco de Ridder,Linda L. Stephens,Abraham Louw,Gregory L. Blatch,Aileen Boshoff

The Malarial Drug Target Plasmodium falciparum 1-Deoxy-D-Xylulose-5- Phosphate Reductoisomerase (PfDXR): Development of a 3-D Model for Identification of Novel, Structural and Functional Features and for Inhibitor Screening (Supplementary Information)

Journal: Protein & Peptide Letters
Volume: 17 Issue: 1 Year: 2010 Page: 109-120
Author(s): Jessica L. Goble, Matthew R. Adendorff, Tjaart A.P. de Beer, Linda L. Stephens, Gregory L. Blatch

Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (Dxr): A Review of the Synthesis and Biological Evaluation of Recent Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 7 Year: 2012 Page: 706-728
Author(s): Emily R. Jackson,Cynthia S. Dowd

Targeting Plasmodium Metabolism to Improve Antimalarial Drug Design

Journal: Current Protein & Peptide Science
Volume: 17 Issue: 3 Year: 2016 Page: 260-274
Author(s): Claudia Avitia-Domínguez,Erick Sierra-Campos,Irene Betancourt-Conde,Miriam Aguirre-Raudry,Alejandra Vázquez-Raygoza,Artemisa Luevano-De la Cruz,Alejandro Favela-Candia,Marie Sarabia-Sanchez,Lluvia Ríos-Soto,Edna Méndez-Hernández,Jorge Cisneros-Martínez,Marcelo Gómez Palacio-Gastélum,Mónica Valdez-Solana,Jessica Hernández-Rivera,Jaime De Lira-Sánchez,Mara Campos-Almazán,Alfredo Téllez-Valencia

Recent Progress in Functional Genomic Research in Plasmodium falciparum

Journal: Current Genomics
Volume: 11 Issue: 4 Year: 2010 Page: 279-286
Author(s): Jianbing Mu, Karl B. Seydel, Adam Bates, Xin-Zhuan Su

Inhibition Studies on Enzymes Involved in Isoprenoid Biosynthesis. Focus on Two Potential Drug Targets: DXR and IDI-2 Enzymes

Journal: Current Enzyme Inhibition
Volume: 7 Issue: 2 Year: 2011 Page: 79-95
Author(s): Jerome de Ruyck, Johan Wouters, C. Dale Poulter

Recent Developments in Antimalarial Drug Discovery

Journal: Anti-Infective Agents in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2006 Page: 105-122
Author(s): A. A. Joshi, C. L. Viswanathan

The Potential of Secondary Metabolites from Plants as Drugs or Leads Against Protozoan Neglected Diseases – Part I

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 14 Year: 2012 Page: 2128-2175
Author(s): T.J. Schmidt, S.A. Khalid, A.J. Romanha, T.MA. Alves, M.W. Biavatti, R. Brun, F.B. Da Costa, S.L. de Castro, V.F. Ferreira,M.V.G. de Lacerda, J.H.G. Lago, L.L. Leon, N.P. Lopes, R.C. das Neves Amorim, M. Niehues, I.V. Ogungbe,A.M. Pohlit, M.T. Scotti, W.N. Setzer, M. de N.C. Soeiro, M. Steindel and A.G. Tempone

Antimalarial Drugs and their Useful Therapeutic Lives: Rational Drug Design Lessons from Pleiotropic Action of Quinolines and Artemisinins

Journal: Current Drug Discovery Technologies
Volume: 7 Issue: 4 Year: 2010 Page: 280-316
Author(s): Francis W. Muregi

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