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Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

Journal: Current Drug Metabolism
Volume: 8 Issue: 1 Year: 2007 Page: 33-45
Author(s): Zoe E. Barter, Martin K. Bayliss, Philip H. Beaune, Alan R. Boobis, David J. Carlile, Robert J. Edwards, J. Brian Houston, Brian G. Lake, John C. Lipscomb, Olavi R. Pelkonen, Geoffrey T. Tucke, Amin Rostami-Hodjegan

Predicting Pediatric Drug Disposition-Present and Future Directions of Pediatric Physiologically-Based Pharmacokinetics

Journal: Drug Metabolism Letters
Volume: 9 Issue: 2 Year: 2015 Page: 80-87
Author(s): Shogo John Miyagi,Janel R. Long-Boyle

Review Article

In Vitro-In Vivo Correlation Using In Silico Modeling of Physiological Properties, Metabolites, and Intestinal Metabolism

Journal: Current Drug Metabolism
Volume: 18 Issue: 1 Year: 2017 Page: 973-982
Author(s): Sung-min Choi,Chin-Yang Kang,Beom-Jin Lee,Jun-Bom Park

Ontogeny of Hepatic Glucuronidation; Methods and Results

Journal: Current Drug Metabolism
Volume: 13 Issue: 6 Year: 2012 Page: 728-743
Author(s): Elke H.J. Krekels, Meindert Danhof, Dick Tibboel, Catherijne A.J. Knibbe

Methodologies for Investigating Drug Metabolism at the Early Drug Discovery Stage: Prediction of Hepatic Drug Clearance and P450 Contribution

Journal: Current Drug Metabolism
Volume: 11 Issue: 8 Year: 2010 Page: 678-685
Author(s): Chie Emoto, Norie Murayama, Amin Rostami-Hodjegan, Hiroshi Yamazaki

Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas

Why We Need Proper PBPK Models to Examine Intestine and Liver Oral Drug Absorption

Journal: Current Drug Metabolism
Volume: 14 Issue: 1 Year: 2013 Page: 57-79
Author(s): Edwin C.Y. Chow,K. Sandy Pang

Sex Differences in the Clearance of CYP3A4 Substrates: Exploring Possible Reasons for the Substrate Dependency and Lack of Consensus

Journal: Current Drug Metabolism
Volume: 13 Issue: 6 Year: 2012 Page: 778-786
Author(s): Manoranjenni Chetty, Donald Mattison, Amin Rostami-Hodjegan

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