Search Result "MEK"


Recent Advances of MEK Inhibitors and Their Clinical Progress

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1364-1378
Author(s): Wang John (Yuan), Wilcoxen M. Keith, Nomoto Kenichi, Wu Sara

MEK Inhibitors: A Therapeutic Approach to Targeting the Ras-MAP Kinase Pathway in Tumors

Journal: Current Pharmaceutical Design
Volume: 10 Issue: 1 Year: 2004 Page: 1907-1914
Author(s): Judith S. Sebolt-Leopold

Ras-Induced Resistance to Lapatinib is Overcome by MEK Inhibition

Journal: Current Cancer Drug Targets
Volume: 10 Issue: 2 Year: 2010 Page: 168-175
Author(s): G. Zoppoli, E. Moran, D. Soncini, M. Cea, A. Garuti, I. Rocco, G. Cirmena, V. Grillo, L. Bagnasco, G. Icardi, F. Ansaldi, S. Parodi, F. Patrone, A. Ballestrero, A. Nencioni

MEK Inhibition Increases Lapatinib Sensitivity Via Modulation of FOXM1

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2013 Page: 2486-2499
Author(s): S.S. Gayle, R.C. Castellino, M.C. Buss, R. Nahta

Potential Role of MEK Inhibition in Treating Patients with Colorectal Cancer

Journal: Current Cancer Therapy Reviews
Volume: 10 Issue: 1 Year: 2014 Page: 34-38
Author(s): Paul Brittain, S. Gail Eckhardt, Christopher H. Lieu

RAS/RAF/MEK Inhibitors in Oncology

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 8 Year: 2012 Page: 1164-1176
Author(s): , M. Broggini

Recent Developments in Targeted Therapies of the RAF-MEK and PI3KAKT Pathways in Cancer Treatment

Journal: Current Cancer Therapy Reviews
Volume: 8 Issue: 3 Year: 2012 Page: 205-217
Author(s): Lobke G.M. Cremers, Johannes Boonstra

Beyond Single Pathway Inhibition: MEK Inhibitors as a Platform for the Development of Pharmacological Combinations with Synergistic Anti-Leukemic Effects

Journal: Current Pharmaceutical Design
Volume: 11 Issue: 2 Year: 2005 Page: 2779-2795
Author(s): M. Milella, C. M. Precupanu, C. Gregorj, M. R. Ricciardi, M. T. Petrucci, S. M. Kornblau, A. Tafuri, M. Andreeff

Review Article

Nanosized Modification Strategies for Improving the Antitumor Efficacy of MEK Inhibitors

Journal: Current Drug Targets
Volume: 21 Issue: 3 Year: 2020 Page: 228-251
Author(s): Yanan Li,Qingrong Dong,Ting Mei,Meichen Zheng,Ramasamy Raj Kumar,Bin Yu,Chunsheng Wu,Hui Zhang,Feifei An

Progress Towards Therapeutic Small Molecule MEK Inhibitors for Use in Cancer Therapy

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 2 Year: 2005 Page: 215-229
Author(s): Eli M. Wallace, Joseph P. Lyssikatos, Tammie Yeh, James D. Winkler, Kevin Koch

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