Search Result "GEF"


Research Article

Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 6 Year: 2014 Page: 840-851
Author(s): Georgina A. Cardama,Maria J. Comin,Leandro Hornos,Nazareno Gonzalez,Lucas Defelipe,Adrian G. Turjanski,Daniel F. Alonso,Daniel E. Gomez,Pablo Lorenzano Menna

Characterization of an mDock5-Specific Antibody and Tissue-Specific Expression and Subcellular Localization of mDock5

Journal: Protein & Peptide Letters
Volume: 17 Issue: 4 Year: 2010 Page: 485-491
Author(s): Eunmin Kim, Jong-Bok Yoon, SungJoo Kim Yoon

RhoGEFs in Cell Motility: Novel Links Between Rgnef and Focal Adhesion Kinase

Journal: Current Molecular Medicine
Volume: 14 Issue: 2 Year: 2014 Page: 221-234
Author(s): N.L.G. Miller,E.G. Kleinschmidt,D.D. Schlaepfer

Research Article

SLN Mediate Active Delivery of Gefitinib into A549 Cell Line: Optimization, Biosafety, and Cytotoxicity Studies

Journal: Drug Delivery Letters
Volume: 13 Issue: 2 Year: 2023 Page: 133-150
Author(s): Abdelrahman Y. Sherif,Gamaleldin I. Harisa,Fars K. Alanazi

Research Article

Optimization of Solid Lipid Nanoparticles and Nanostructured Lipidic Carriers as Promising Delivery for Gefitinib: Characterization and In-vitro Evaluation

Journal: Current Drug Therapy
Volume: 16 Issue: 2 Year: 2021 Page: 170-183
Author(s): Akshat Shah,Asha Patel,Abhay Dharamsi

Structure-Function Based Design of Small Molecule Inhibitors Targeting Rho Family GTPases

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 1109-1116
Author(s): Nicolas Nassar, Jose Cancelas, Jie Zheng, David A. Williams, Yi Zheng

Research Article

Design of Experiments (DoE) Approach to Optimize the Sustained Release Microparticles of Gefitinib

Journal: Current Drug Delivery
Volume: 16 Issue: 4 Year: 2019 Page: 364-374
Author(s): Govind Soni,Khushwant S. Yadav,M. K. Gupta

Ubiquitination in Rho Signaling

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 2 Year: 2011 Page: 2879-2887
Author(s): Feng Ding, Zhenyu Yin, Hong-Rui Wang

Rho-Signaling Pathways in Chronic Myelogenous Leukemia

Journal: Cardiovascular & Hematological Disorders-Drug Targets
Volume: 8 Issue: 4 Year: 2008 Page: 261-267
Author(s): Katerina Kuzelova, Zbynek Hrkal

Rho-Kinase and RGS-Containing RhoGEFs as Molecular Targets for the Treatment of Erectile Dysfunction

Journal: Current Pharmaceutical Design
Volume: 11 Issue: 3 Year: 2005 Page: 4029-4040
Author(s): A. E. Linder, R. C. Webb, T. M. Mills, Z. Ying, R. W. Lewis, C. E. Teixeira

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