Search Result "FLIPR"


Identification and Characterization of mGlu3 Ligands Using a High Throughput FLIPR Assay for Detection of Agonists, Antagonists, and Allosteric Modulators

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 7 Year: 2011 Page: 631-641
Author(s): Steven D. Pratt, Mario Mezler, Herve Geneste, Margot H.M. Bakker, Philip J. Hajduk, Sujatha M. Gopalakrishnan

Chimeric and Promiscuous G Proteins in Drug Discovery and the Deorphanization of GPCRs

Journal: Drug Design Reviews - Online (Discontinued)
Volume: 2 Issue: 1 Year: 2005 Page: 66-79
Author(s): David C. New, Yung H. Wong

Measuring Intracellular Calcium Fluxes in High Throughput Mode

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 4 Year: 2003 Page: 355-362
Author(s): Chris Chambers, Fiona Smith, Christine Williams, Sandra Marcos, Zhen Han Liu, Paul Hayter, Giuseppe Ciaramella, Wilma Keighley, Phil Gribbon, Andreas Sewing

Development and Validation of a Fluorescence-Based HTS Assay for the Identification of P/Q-Type Calcium Channel Blockers

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 15 Issue: 5 Year: 2012 Page: 372-385
Author(s): Mario Mezler,David Hermann,Andrew M. Swensen,Andreas Draguhn,Georg C. Terstappen,Gerhard Gross,Hans Schoemaker,Gail Freiberg,Steve Pratt,Sujatha M. Gopalakrishnan,Volker Nimmrich

3D-QSAR Based Pharmacophore Modeling and Virtual Screening for Identification of Novel G Protein-Coupled Receptor40 Agonists

Journal: Current Computer-Aided Drug Design
Volume: 11 Issue: 1 Year: 2015 Page: 51-56
Author(s): Peng Lu,Yubin Wang,Ping Kai Ouyang,Jinxiong She,Mingfang He

Development of a Novel High-Throughput Assay for the Investigation of GlyT-1b Neurotransmitter Transporter Function

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 1 Year: 2006 Page: 9-14
Author(s): Lynda Allan, J. L. Leith, Marianthi Papakosta, John A. Morrow, Nicholas G. Irving, Brian W. McFerran, Alan G. Clark

Research Article

Establishment of a High Throughput Screening System for GABAA1Modulators in Living Cells

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 26 Issue: 4 Year: 2023 Page: 801-815
Author(s):

Characterization of Substituted Phenylpropylamides as Highly Selective Agonists at the Melatonin MT2 Receptor

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 2 Year: 2013 Page: 289-300
Author(s): King H. Chan,Yueqing Hu,Maurice K. C. Ho,Yung H. Wong

Pharmacological Characterization of Ligands at Recombinant NMDA Receptor Subtypes by Electrophysiological Recordings and Intracellular Calcium Measurements

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 4 Year: 2008 Page: 304-315
Author(s): Kasper B. Hansen, Hans Brauner-Osborne, Jan Egebjerg

Positive Allosteric Modulators for mGluR2 Receptors: A Medicinal Chemistry Perspective

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 15 Year: 2014 Page: 1771-1788
Author(s): Gyorgy Szabo,Gyorgy Miklos Keseru

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