Search Result "5-LOX"


QSAR and Docking Studies on Propenone Derivatives as Dual COX and 5- LOX Inhibitors

Journal: Letters in Organic Chemistry
Volume: 5 Issue: 7 Year: 2008 Page: 544-554
Author(s): Ponnurengam M. Sivakumar, Sethu K. Geetha Babu, Vaibhav Sharma, Mukesh Doble

Structure and Ligand Based Drug Design Strategies in the Development of Novel 5- LOX Inhibitors

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2012 Page: 3763-3778
Author(s): Polamarasetty Aparoy, Kakularam Kumar Reddy, Pallu Reddanna

New Trends in Dual 5-LOX / COX Inhibition

Journal: Current Medicinal Chemistry
Volume: 9 Issue: 9 Year: 2002 Page: 941-962
Author(s): Xavier de Leval, Fabien Julemont, Jacques Delarge, Bernard Pirotte, Jean-Michel Dogne

Research Article

Design of Dual COX-2 and 5-LOX Inhibitors with Iron-Chelating Properties Using Structure-Based and Ligand-Based Methods

Journal: Letters in Drug Design & Discovery
Volume: 18 Issue: 0 Year: 2021 Page: 1-14
Author(s): Jelena Bošković,Dušan Ružić,Olivera Čudina,Katarina Nikolic,Vladimir Dobričić

The 5-lipoxygenase (5-LOX) Inhibitor Zileuton Reduces Inflammation and Infarct Size with Improvement in Neurological Outcome Following Cerebral Ischemia

Journal: Current Neurovascular Research
Volume: 12 Issue: 4 Year: 2015 Page: 398-403
Author(s): Bruno Costa Silva, Aline Silva de Miranda, Flavia Guimaraes Rodrigues, Ana Leticia Malheiros Silveira, Gustavo Henrique de Souza Resende, Marcio Flavio Dutra Moraes, Antonio Carlos Pinheiro de Oliveira, Patricia Martins Parreiras, Luciola da Silva Barcelos, Mauro Martins Teixeira, Fabiana Simao Machado, Antonio Lucio Teixeira, Milene Alvarenga Rachid

Recent Development in the Field of Dual COX / 5-LOX Inhibitors

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 4 Issue: 6 Year: 2004 Page: 633-638
Author(s): Fabien Julemont, Jean-Michel Dogne, Bernard Pirotte, Xavier de Leval

5-Lipoxygenase in the Central Nervous System: Therapeutic Implications

Journal: Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents
Volume: 1 Issue: 2 Year: 2002 Page: 115-121
Author(s): Hari Manev, Tolga Uz

The Co-regulatory Role of 5-Lipoxygenase and Cyclooxygenase-2 in the Carcinogenesis and their Promotion by Cigarette Smoking in Colons

Journal: Current Medicinal Chemistry
Volume: 23 Issue: 1 Year: 2016 Page: 1131-1138
Author(s): J. Shen, W.X. Li, Z.G. Xiao, L. Zhang, M.X. Li, L.F. Li, W. Hu, L. Lu, F. Boudreau, C.H. Cho

Synthesis and Antioxidant Activity of Novel Quinazolinones Functionalized with Urea/Thiourea/Thiazole Derivatives as 5-Lipoxygenase Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 11 Issue: 6 Year: 2014 Page: 712-720
Author(s): Maralekere K. Prashanth, Hosakere D. Revanasiddappa

COX-2/5-LOX Dual Acting Anti-Inflammatory Drugs in Cancer Chemotherapy

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 3 Year: 2007 Page: 283-296
Author(s): Laurence Goossens, Nicole Pommery, Jean Pierre Henichart

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