Search Result "reactive metabolite"


Are Chemically Reactive Metabolites Responsible for Adverse Reactions to Drugs?

Journal: Current Drug Metabolism
Volume: 3 Issue: 4 Year: 2002 Page: 351-366
Author(s): D. P. Williams, N. R. Kitteringham, D. J. Naisbitt, M. Pirmohamed, D. A. Smith, B. K. Park

On Mechanisms of Reactive Metabolite Formation from Drugs

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 13 Issue: 5 Year: 2013 Page: 720-729
Author(s): Alf Claesson, Ola Spjuth

Extrahepatic Targets and Cellular Reactivity of Drug Metabolites

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 4 Year: 2015 Page: 408-437
Author(s): Hilmi Orhan

A New Quaternary Ammonium Cysteine Analogue as a Trapping Reagent for Reactive Metabolites Screening

Journal: Drug Metabolism Letters
Volume: 8 Issue: 1 Year: 2014 Page: 36-42
Author(s): Natalia Penner, Xiaojing Liu, Chandra Prakash

Review Article

Reactive Metabolites: Generation and Estimation with Electrochemistry Based Analytical Strategy as an Emerging Screening Tool

Journal: Current Analytical Chemistry
Volume: 16 Issue: 7 Year: 2020 Page: 811-825
Author(s): Maria Bandookwala,Kavya Sri Nemani,Bappaditya Chatterjee,Pinaki Sengupta

Gauging Reactive Metabolites in Drug-Induced Toxicity

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 4 Year: 2015 Page: 465-489
Author(s): Marsha R. Eno, Michael D. Cameron

Mechanism of Idiosyncratic Drug Reactions: Reactive Metabolites Formation, Protein Binding and the Regulation of the Immune System

Journal: Current Drug Metabolism
Volume: 3 Issue: 4 Year: 2002 Page: 367-377
Author(s): C. Ju, J. P. Uetrecht

In Vitro Screening Techniques for Reactive Metabolites for Minimizing Bioactivation Potential in Drug Discovery

Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 952-964
Author(s): Chandra Prakash, Raman Sharma, Michelle Gleave, Angus Nedderman

Xenobiotic Acyl Glucuronides and Acyl CoA Thioesters as Protein- Reactive Metabolites With the Potential to Cause Idiosyncratic Drug Reactions

Journal: Current Drug Metabolism
Volume: 3 Issue: 4 Year: 2002 Page: 439-450
Author(s): Urs A. Boelsterli

Cyclic Metabolites: Chemical and Biological Considerations

Journal: Current Drug Metabolism
Volume: 9 Issue: 2 Year: 2008 Page: 175-188
Author(s): John C.L. Erve

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