Search Result "mechanism-based inactivation."


Research Article

Oxypeucedanin is a Mechanism-Based Inactivator of CYP2B6 and CYP2D6

Journal: Current Drug Metabolism
Volume: 22 Issue: 0 Year: 2021 Page: 1-11
Author(s): Kehan Zhang,Yilin Li,Yao Fu,Tiantian Cui,Qian Wang,Xu Mao,Ying Peng,Jiang Zheng

Molecular Analysis and Modeling of Inactivation of Human CYP2D6 by Four Mechanism Based Inactivators

Journal: Drug Metabolism Letters
Volume: 6 Issue: 1 Year: 2012 Page: 7-14
Author(s): Mara Livezey, Leslie D. Nagy, Laura E. Diffenderfer, Evan J. Arthur, David J. Hsi, Jeffrey M. Holton, Laura Lowe Furge

Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Chemical Mechanisms, Structure-Activity Relationships and Relationship to Clinical Drug-Drug Interactions and Idiosyncratic Adverse Drug Reactions

Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 407-447
Author(s): Amit S. Kalgutkar, R. Scott Obach, Tristan S. Maurer

Mechanism-Based Inactivators as Probes of Cytochrome P450 Structure and Function

Journal: Current Drug Metabolism
Volume: 2 Issue: 3 Year: 2001 Page: 215-243
Author(s): Ute M. Kent, Monica I. Jushchhyshyn, Paul F. Hollenberg

Prediction of Drug-Drug Interactions Arising From Mechanism-Based Inactivation: Key Input Parameters and Impact on Risk Assessment

Journal: Current Drug Metabolism
Volume: 12 Issue: 9 Year: 2011 Page: 871-890
Author(s): Simon G. Wong

Integrating In Vitro Kinetic Data from Compounds Exhibiting Induction, Reversible Inhibition and Mechanism-Based Inactivation: In Vitro Study Design

Journal: Current Drug Metabolism
Volume: 5 Issue: 2 Year: 2004 Page: 141-146
Author(s): Donavon J. McConn, Zhiyang Zhao

Drug-Drug Interactions via Mechanism-Based Cytochrome P450 Inactivation: Points to Consider for Risk Assessment from In Vitro Data and Clinical Pharmacologic Evaluation

Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 449-462
Author(s): Karthik Venkatakrishnan, R. Scott Obach

Assessment of the Inactivation Potential of Desethylamiodarone on Human CYP1A1

Journal: Drug Metabolism Letters
Volume: 4 Issue: 1 Year: 2010 Page: 9-14
Author(s): Marwa E. Elsherbiny, Ayman O.S. El-Kadi, Dion R. Brocks

Advances in the Development of Inactivated Virus Vaccines

Journal: Recent Patents on Anti-Infective Drug Discovery
Volume: 1 Issue: 3 Year: 2006 Page: 291-296
Author(s): Fausto Stauffer, Tatiana El-Bacha, Andrea T. Da Poian

Photodynamic Inactivation of Bacteria

Journal: Current Bioactive Compounds
Volume: 2 Issue: 2 Year: 2006 Page: 127-142
Author(s): Edgardo N. Durantini

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