Search Result "extended clearance model"


Review Article

Physiologically-based Pharmacokinetic (PBPK) Modelling of Transporter Mediated Drug Absorption, Clearance and Drug-drug Interactions

Journal: Current Drug Metabolism
Volume: 22 Issue: 7 Year: 2021 Page: 523-531
Author(s): Kunal S. Taskar,Isobel Harada,Ravindra V. Alluri

Covariates of Amikacin Clearance in Neonates: The Impact of Postnatal Age on Predictability

Journal: Drug Metabolism Letters
Volume: 2 Issue: 4 Year: 2008 Page: 286-289
Author(s): Karel Allegaert, Isabelle Scheers, Veerle Cossey, Brian J. Anderson

ARC - Augmented Renal Clearance

Journal: Current Pharmaceutical Biotechnology
Volume: 12 Issue: 1 Year: 2011 Page: 2020-2029
Author(s): Andrew A. Udy, Michael T. Putt, Robert J. Boots, Jeffrey Lipman

Application of Model-Based Approaches to Evaluate Hepatic Transporter-Mediated Drug Clearance: In vitro, In vivo, and In vitro-In vivo Extrapolation

Journal: Current Drug Metabolism
Volume: 17 Issue: 5 Year: 2016 Page: 456-468
Author(s): Zhihao Liu, Kexin Liu

Blood-Brain-Barrier Models for the Investigation of Transporter- and Receptor-Mediated Amyloid-β Clearance in Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 7 Issue: 7 Year: 2010 Page: 578-590
Author(s): T. Pflanzner, C. R. Kuhlmann, C. U. Pietrzik

Smoke Clearance in an Underground Car Park using the Jet Fan System

Journal: Current Environmental Engineering
Volume: 3 Issue: 1 Year: 2016 Page: 6-17
Author(s): Essam E. Khalil, Sherif M. Gomaa

A High Throughput, 384-Well, Semi-Automated, Hepatocyte Intrinsic Clearance Assay for Screening New Molecular Entities in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 18 Issue: 5 Year: 2015 Page: 442-452
Author(s): Lance Heinle, Vincent Peterkin, Sonia M. de Morais, Gary J. Jenkins, Ilaria Badagnani

Granulocyte Apoptosis and Macrophage Clearance of Apoptotic Cells as Targets for Pharmacological Intervention in Inflammatory Diseases

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2006 Page: 3-12
Author(s): Nicola A. Riley, Carol Ward, Deborah A. Sawatzky, Tara A. Sheldrake, Ian Dransfield, Christopher Haslett, Adriano G. Rossi

The Impact of In Vitro Binding on In Vitro - In Vivo Extrapolations, Projections of Metabolic Clearance and Clinical Drug-Drug Interactions

Journal: Current Drug Metabolism
Volume: 7 Issue: 3 Year: 2006 Page: 251-264
Author(s): K. Grime, R. J. Riley

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