Search Result "PBPK models"


Development of a PBPK Model for Monoclonal Antibodies and Simulation of Human and Mice PBPK of a Radiolabelled Monoclonal Antibody

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 9 Year: 2009 Page: 988-1007
Author(s): Tomi Heiskanen, Tomas Heiskanen, Kalevi Kairemo

PBPK Modeling of Intestinal and Liver Enzymes and Transporters in Drug Absorption and Sequential Metabolism

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 743-761
Author(s): Jianghong Fan, Shu Chen, Edwin C.Y. Chow, K. Sandy Pang

Review Article

Physiologically-based Pharmacokinetic (PBPK) Modelling of Transporter Mediated Drug Absorption, Clearance and Drug-drug Interactions

Journal: Current Drug Metabolism
Volume: 22 Issue: 7 Year: 2021 Page: 523-531
Author(s): Kunal S. Taskar,Isobel Harada,Ravindra V. Alluri

Research Article

Using PBPK Modeling to Predict Drug Exposure and Support Dosage Adjustments in Patients With Renal Impairment: An Example with Lamivudine

Journal: Current Drug Discovery Technologies
Volume: 17 Issue: 3 Year: 2020 Page: 387-396
Author(s): Kushal Shah,Briann Fischetti,Agnes Cha,David R. Taft

Research Article

The Development of a PBPK Model for Atomoxetine Using Levels in Plasma, Saliva and Brain Extracellular Fluid in Patients with Normal and Deteriorated Kidney Function

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 20 Issue: 0 Year: 2021 Page: 1-13
Author(s): Mo'tasem Mohamed Alsmadi,Laith Naser AL-Eitan,Nasir Mohammed Idkaidek,Karem Hasan Alzoubi

Why We Need Proper PBPK Models to Examine Intestine and Liver Oral Drug Absorption

Journal: Current Drug Metabolism
Volume: 14 Issue: 1 Year: 2013 Page: 57-79
Author(s): Edwin C.Y. Chow, K. Sandy Pang

General Research Article

In Silico Pharmacokinetic Study of Vancomycin Using PBPK Modeling and Therapeutic Drug Monitoring

Journal: Current Drug Metabolism
Volume: 22 Issue: 2 Year: 2021 Page: 150-162
Author(s): Abigail Ferreira,Helena Martins,José C. Oliveira,Rui Lapa,Nuno Vale

Review Article

PBPK in Preterm and Term Neonates: A Review

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 3 Year: 2017 Page: 5943-5954
Author(s): Robin Michelet,Jan Van Bocxlaer,An Vermeulen

Physiologically-based Pharmacokinetic (PBPK) Models for Assessing the Kinetics of Xenobiotics during Pregnancy: Achievements and Shortcomings

Journal: Current Drug Metabolism
Volume: 13 Issue: 6 Year: 2012 Page: 695-720
Author(s): G. Lu, K. Abduljalil, M. Jamei, T. N. Johnson, H. Soltani, A. Rostami-Hodjegan

Research Article

The Effect of Gastric pH on the Pharmacokinetics-pharmacodynamics of Naphthoquine in Rodents, as well as in Human Predicted Using a PBPK Model

Journal: Current Drug Metabolism
Volume: 22 Issue: 5 Year: 2021 Page: 363-371
Author(s): Yuewu Xie,Huixiang Liu,Xiaoyue Chen,Jie Xing

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