Search Result "NSC23766"


Structure-Function Based Design of Small Molecule Inhibitors Targeting Rho Family GTPases

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 1109-1116
Author(s): Nicolas Nassar, Jose Cancelas, Jie Zheng, David A. Williams, Yi Zheng

Rac-1 as a New Therapeutic Target in Cerebro- and Cardio-Vascular Diseases

Journal: Current Drug Targets
Volume: 15 Issue: 1 Year: 2014 Page: 1231-1246
Author(s): Albino Carrizzo, Maurizio Forte, Maria Lembo, Luigi Formisano, Annibale A. Puca, Carmine Vecchione

Signaling Through Rho GTPase Pathway as Viable Drug Target

Journal: Current Medicinal Chemistry
Volume: 16 Issue: 1 Year: 2009 Page: 1355-1365
Author(s): Qun Lu, Frank M. Longo, Huchen Zhou, Stephen M. Massa, Yan-Hua Chen

GEFT, A Rho Family Guanine Nucleotide Exchange Factor, Regulates Lens Differentiation through a Rac1-Mediated Mechanism

Journal: Current Molecular Medicine
Volume: 11 Issue: 6 Year: 2011 Page: 465-480
Author(s): D. C. Mitchell, B. A. Bryan, L. Liu, X.-H. Hu, X.-Q. Huang, W.-K. Ji, P.-C. Chen, W.-F. Hu, J-P Liu, J. Zhang, M. Liu, D. W.-C. Li

Research Article

Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 6 Year: 2014 Page: 840-851
Author(s): Georgina A. Cardama, Maria J. Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G. Turjanski, Daniel F. Alonso, Daniel E. Gomez, Pablo Lorenzano Menna

Targeting Rho GTPases by Peptidic Structures

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 2 Year: 2009 Page: 2481-2487
Author(s): Filippo Marchioni, Yi Zheng

Review Article

Direct Targeting of the Ras GTPase Superfamily Through Structure- Based Design

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2017 Page: 16-29
Author(s): Wenye Zhao, Mostafa Jamshidiha, Thomas Lanyon-Hogg, Chiara Recchi, Ernesto Cota, Edward W. Tate

Extracellular Superoxide and the Growth of Pancreatic Carcinoma

Journal: Current Cancer Therapy Reviews
Volume: 9 Issue: 4 Year: 2013 Page: 278-283
Author(s): John A. Cieslak, Joseph J. Cullen

Novel Pharmacologic Approaches to the Prevention and Treatment of Ulcerative Colitis

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 1 Year: 2013 Page: 17-28
Author(s): Xiaoming Deng, Sandor Szabo, Tetyana Khomenko, Ganna Tolstanova, Brankica Paunovic, Samuel W. French, Zsuzsanna Sandor

The Metastatic Process: Methodological Advances and Pharmacological Challenges

Journal: Current Medicinal Chemistry
Volume: 16 Issue: 1 Year: 2009 Page: 1704-1717
Author(s): Antonio Mazzocca, Vinicio Carloni

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