Search Result "JAK2-specific inhibitors"


The Recent Medicinal Chemistry Development of Jak2 Tyrosine Kinase Small Molecule Inhibitors

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2010 Page: 4551-4558
Author(s): R. Baskin, A. Majumder, P. P. Sayeski

Review Article

Searching for Novel Janus Kinase-2 Inhibitors Using a Combination of Pharmacophore Modeling, 3D-QSAR Studies and Virtual Screening

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2017 Page: 268-294
Author(s): Eleni Vrontaki,Georgia Melagraki,Antreas Afantitis,Thomas Mavromoustakos,George Kollias

A Structure-Function Perspective of Jak2 Mutations and Implications for Alternate Drug Design Strategies: The Road not Taken

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 3 Year: 2011 Page: 4659-4673
Author(s): K. Gnanasambandan, P.P. Sayeski

The Use of Structural Biology in Janus Kinase Targeted Drug Discovery

Journal: Current Drug Targets
Volume: 12 Issue: 4 Year: 2011 Page: 546-555
Author(s): Nilda L. Alicea-Velazquez, Titus J. Boggon

Jak2 Tyrosine Kinase and Cancer: How Good Cells Get HiJAKed

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 7 Issue: 6 Year: 2007 Page: 643-650
Author(s): Michael D. Godeny, Peter P. Sayeski

JAK Inhibitors: Pharmacology and Clinical Activity in Chronic Myeloprolipherative Neoplasms

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 9 Year: 2013 Page: 1147-1161
Author(s): J. Trelinski, T. Robak

Research Article

A Phenotypic Screen for Small-Molecule Inhibitors of Constitutively Active Mutant Thrombopoietin Receptor Implicated in Myeloproliferative Neoplasms

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 19 Issue: 1 Year: 2016 Page: 824-833
Author(s): Anna Ngo, Ann Zhufang Koay, Christian Pecquet, Carmen C. Diaconu, Yasmine Ould-Amer, Qiwei Huang, Congbao Kang, Anders Poulsen, May Ann Lee, David Jenkins, Andrew Shiau, Stefan N. Constantinescu, Meng Ling Choong

In silico Designing and Screening of Lead Compounds to NS5-Methyltransferase of Dengue Viruses

Journal: Medicinal Chemistry
Volume: 7 Issue: 6 Year: 2011 Page: 655-662
Author(s): Dakshinamurthy Sivakumar, Thirunavukkarasu Sivaraman

Review Article

An Update on JAK Inhibitors

Journal: Current Medicinal Chemistry
Volume: 26 Issue: 1 Year: 2019 Page: 1806-1832
Author(s): Francesca Musumeci,Chiara Greco,Ilaria Giacchello,Anna Lucia Fallacara,Munjed M. Ibrahim,Giancarlo Grossi,Chiara Brullo,Silvia Schenone

Tyrosine Kinases as Therapeutic Targets in BCR-ABL Negative Chronic Myeloproliferative Disorders

Journal: Current Drug Targets
Volume: 8 Issue: 2 Year: 2007 Page: 205-216
Author(s): Andreas Reiter, Christoph Walz, Nicholas C. P. Cross

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