Search Result "Differential Scanning Fluorimetry (DSF)"

Research Article

Characterization of P. aeruginosa Glucose 6- Phosphate Isomerase: A Functional Insight via In-Vitro Activity Study

Journal: Current Topics in Medicinal Chemistry
Volume: 20 Issue: 2 Year: 2020 Page: 2651-2661
Author(s): Deekshi Angira,Nalini Natarajan,Samir R. Dedania,Darshan H. Patel,Vijay Thiruvenkatam

Computational Sampling and Simulation Based Assessment of Novel Mycobacterium tuberculosis Glutamine Synthetase Inhibitors: Study Involving Structure Based Drug Design and Free Energy Perturbation

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 9 Year: 2016 Page: 978-995
Author(s): Priyanka Suryadevara, Perumal Yogeeswari, Vijay Soni, Parthiban Brindha Devi, Vinay Kumar Nandicoori, Dharmarajan Sriram

Research Article

Lead Generation for Human Mitotic Kinesin Eg5 using Structure-based Virtual Screening and Validation by in vitro and Cell-based Assays

Journal: Current Computer-Aided Drug Design
Volume: 16 Issue: 0 Year: 2020 Page: 1-13
Author(s): Himesh Makala,Soundarya Priya Alexandar,Devipriya Nagarajan,Santanu Kar Mahapatra,Venkatasubramanian Ulaganathan

Research Article

Improving the Hsp90 Inhibitors Containing 4-(2,4-Dihydroxyphenyl)-1,2,3-thiadiazole Scaffold: Synthesis, Affinity and Effect on Cancer Cells

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2017 Page: 1593-1603
Author(s): Egidijus Kazlauskas, Algirdas Brukstus, Herkus Petrikas, Vilma Petrikaite, Inga Cikotiene, Daumantas Matulis

Crystal Structure of the Pseudomonas aeruginosa MurG: UDP-GlcNAc Substrate Complex

Journal: Protein & Peptide Letters
Volume: 20 Issue: 9 Year: 2013 Page: 1002-1008
Author(s): Kieron Brown, Sarah C.M. Vial, Neesha Dedi, James Westcott, Stephen Scally, Timothy D.H. Bugg, Peter A. Charlton, Graham M.T. Cheetham

Fragment Based Drug Discovery Using Fluorescence Correlation Spectroscopy Techniques: Challenges and Solutions

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1582-1591
Author(s): T. Hesterkamp, J. Barker, A. Davenport, M. Whittaker

Phenylalanine Hydroxylase Misfolding and Pharmacological Chaperones

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 2 Year: 2012 Page: 2534-2545
Author(s): Jarl Underhaug, Oscar Aubi, Aurora Martinez

From HTS to Phase I: The Institute for Therapeutics Discovery and Development at the University of Minnesota

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 3 Year: 2014 Page: 231-240
Author(s): Peter I. Dosa, Gunda I. Georg, Vadim J. Gurvich, Jon E. Hawkinson, Michael A. Walters, Henry L. Wong

Methods of High Throughput Biophysical Characterization in Biopharmaceutical Development

Journal: Current Drug Discovery Technologies
Volume: 10 Issue: 1 Year: 2013 Page: 59-70
Author(s): Vladimir I. Razinkov, Michael J. Treuheit, Gerald W. Becker

Review Article

Updated Research and Applications of Small Molecule Inhibitors of Keap1-Nrf2 Protein-Protein Interaction: a Review

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 1 Year: 2014 Page: 1861-1870
Author(s): Chunlin Zhuang, Zhenyuan Miao, Chunquan Sheng, Wannian Zhang

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