Search Result "Bcl-xL"


Review Article

Homology Modeling and Docking Studies of Bcl-2 and Bcl-xL with Small Molecule Inhibitors: Identification and Functional Studies

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 3 Year: 2018 Page: 2633-2663
Author(s): Abdul Ajees Abdul Salam,Upendra Nayek,Dhanya Sunil

Small Molecule Inhibition of the Bcl-XL-BH3 Protein-Protein Interaction: Proof-of-Concept of an In Vivo Chemopotentiator ABT-737

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 961-965
Author(s): Shaun R. Stauffer

Site-directed Mutagenesis Study of the Ile140 in Conserved Hydrophobic Core of Bcl-xL

Journal: Protein & Peptide Letters
Volume: 19 Issue: 9 Year: 2012 Page: 991-996
Author(s): Xin Zhang, Ying Tan, Rui Zhao, Bizhu Chu, Chunyan Tan, Yuyang Jiang

Research Article

Acetogenins Exhibit Potential BCL-XL Inhibitor for the Induction of Apoptosis in the Molecular Docking Study

Journal: Current Drug Discovery Technologies
Volume: 18 Issue: 0 Year: 2021 Page: 1-11
Author(s): Noraziah Nordin,Kaynat Khimani,Mohd Faiz Abd Ghani

Research Article

Development and Validation of a Robust QSAR Model for Benzothiazole Hydrazone Derivatives as Bcl-XL Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 16 Issue: 1 Year: 2019 Page: 11-20
Author(s): Pawan Gupta,Aleksandrs Gutcaits

Zebrafish Stem Cell Differentiation Stage Factors Suppress Bcl-xL Release and Enhance 5-Fu-Mediated Apoptosis in Colon Cancer Cells

Journal: Current Pharmaceutical Biotechnology
Volume: 12 Issue: 2 Year: 2011 Page: 261-267
Author(s): F. DAnselmi, A. Cucina, P. M. Biava, S. Proietti, P. Coluccia, L. Frati, M. Bizzarri

Preliminary Studies on the Activity of Mixed Polyphenol-Heterocyclic Systems Against B16-F10 Melanoma Cancer Cells

Journal: Medicinal Chemistry
Volume: 12 Issue: 5 Year: 2016 Page: 419-425
Author(s):

Identification of Novel Potent Inhibitors Against Bcl-xL Anti-apoptotic Protein Using Docking Studies

Journal: Protein & Peptide Letters
Volume: 19 Issue: 1 Year: 2012 Page: 1302-1317
Author(s): Gupta Shipra, Misra Gauri, Pant Mohan Chandra, Seth Prahlad Kishore

Review Article

Recent Advances in Cancer Drug Development: Targeting Induced Myeloid Cell Leukemia-1 (Mcl-1) Differentiation Protein

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 4 Year: 2017 Page: 4488-4514
Author(s): Mohammad Abid,Yogesh A. Sonawane,Jacob I. Contreras,Sandeep Rana,Amarnath Natarajan

Small-Molecule Inhibitors of Bcl-2 Family Proteins as Therapeutic Agents in Cancer

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 3 Issue: 1 Year: 2008 Page: 20-30
Author(s): Ramzi Mohammad, Anshu Giri, Anton-Scott Goustin

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