Search Result "3��-hydroxysteroid dehydrogenase"


Synthesis and Biochemical Evaluation of a Series of Methanesulfonate Derivatives of 4-Hydroxyphenyl Ketone as Probes of the Active Site of Type 3 OF 17β-Hydroxysteroid Dehydrogenase Family of Enzymes

Journal: Letters in Drug Design & Discovery
Volume: 6 Issue: 7 Year: 2009 Page: 518-523
Author(s): Kruti Shah, Moniola S. Olusanjo, Tim Cartledge, Caroline P. Owen, Sabbir Ahmed

Estrone (E1) Based Esters as Potential Inhibitors of Type 3 17β- hydroxysteroid Dehydrogenase (17β-HSD3) in the Treatment of Hormone-Dependent Prostate Cancer

Journal: Letters in Drug Design & Discovery
Volume: 7 Issue: 9 Year: 2010 Page: 650-656
Author(s): Moniola S. Olusanjo, Sabbir Ahmed

Synthesis, Biochemical Evaluation and Rationalisation of a Series of (3-O-Sulfonate) Derivatives of Estrone (E1) as Probes of the Active Site of Type 3 of the 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Family of Enzymes

Journal: Letters in Drug Design & Discovery
Volume: 9 Issue: 1 Year: 2012 Page: 69-76
Author(s): Mohsen Akbarzadeh, Moniola S. Olusanjo, Sabbir Ahmed

Research Article

17β-N-arylcarbamoylandrost-4-en-3-one Derivatives as Inhibitors of the Enzymes 3α-Hydroxysteroid Dehydrogenase and 5α-Reductase

Journal: Current Enzyme Inhibition
Volume: 14 Issue: 1 Year: 2018 Page: 36-50
Author(s): Eugene Bratoeff,Isabel Moreno,Francisco Cortes-Benitez,Yvonne Heuze,Marisol Bravo,Marisa Cabeza

Design, Synthesis and In Vitro Evaluation of 4-Androstene-3,17-dione/Adenosine Hybrid Compounds as Bisubstrate Inhibitors of Type 3 17β-Hydroxysteroid Dehydrogenase

Journal: Medicinal Chemistry
Volume: 2 Issue: 4 Year: 2006 Page: 329-347
Author(s): Marie Berube, Yannick Laplante, Donald Poirier

Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels

Journal: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Volume: 1 Issue: 2 Year: 2007 Page: 103-118
Author(s): Michael L. Mohler, Ramesh Narayanan, Yali He, Duane D. Miller, James T. Dalton

Research Article

Insight into the Mechanism of 17β-Hydroxysteroid Dehydrogenase Type 3 Inhibition by the Androsterone Derivative RM-532-105

Journal: Current Enzyme Inhibition
Volume: 16 Issue: 3 Year: 2020 Page: 243-250
Author(s): Preyesh Stephen,Jenny Roy,René Maltais,Donald Poirier

Esters of Dehydroepiandrosterone (DHEA) as Probes for the Active Site of Type 3 17β-Hydroxysteroid Dehydrogenase (17β-HSD3)

Journal: Letters in Drug Design & Discovery
Volume: 7 Issue: 5 Year: 2010 Page: 365-369
Author(s): Moniola S. Olusanjo, Caroline P. Owen, Sabbir Ahmed

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