Synthesis and Biological Applications of Glycoconjugates

Cyclopeptide-Based Glycoclusters

Author(s): Olivier Renaudet, Didier Boturyn, Pascal Dumy

Pp: 129-144 (16)

DOI: 10.2174/978160805277611101010129

* (Excluding Mailing and Handling)

Abstract

The emergence of glycomics has deeply stimulated the design of new bioactive glycoclusters over the past decade. Among the increasing number of multivalent synthetic structures reported so far, cyclopeptide-based glycoclusters (CBGs) have recently shown promising interest for diverse biological applications. This chapter aims at describing the major advances in this field, with a special focus on the inhibition of carbohydrate-protein interactions and the synthetic vaccines.


Keywords: Cyclopeptide, glycocluster, oxime, combinatorial chemistry, synthetic vaccine, lectin

Related Journals
Related Books
© 2024 Bentham Science Publishers | Privacy Policy