Search Result "PIM-1"


Research Article

Identification of Pim-1 Kinase Inhibitors by Pharmacophore Model, MolecularDocking-based Virtual Screening, and Biological Evaluation

Journal: Current Computer-Aided Drug Design
Volume: 18 Issue: 3 Year: 2022 Page: 240-246
Author(s):

New Potent and Selective Inhibitor of Pim-1/3 Protein Kinases Sensitizes Human Colon Carcinoma Cells to Doxorubicin

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 9 Year: 2014 Page: 1228-1236
Author(s): Pascale Moreau,Lyubov G. Dezhenkova,Fabrice Anizon,Lionel Nauton,Vincent Thery,Shuguang Liang,Dmitry N. Kaluzhny,Alexander A. Shtil

Research Article

New Mechanistic Insight on the PIM-1 Kinase Inhibitor AZD1208 Using Multidrug Resistant Human Erythroleukemia Cell Lines and Molecular Docking Simulations

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 1 Year: 2019 Page: 914-926
Author(s): Maiara Bernardes Marques,Michael González-Durruthy,Bruna Félix da Silva Nornberg,Bruno Rodrigues Oliveira,Daniela Volcan Almeida,Ana Paula de Souza Votto,Luis Fernando Marins

Density Functional Theory, Docking, Bioisosteric Replacement, Pharmacophore Perception, Physical Chemical Analyses of the Interactions of Novel PIM-1 Inhibitors with Suitable Pharmacokinetic Properties for Cancer Treatment

Journal: Current Physical Chemistry
Volume: 3 Issue: 4 Year: 2013 Page: 408-412
Author(s): Luiz R. G. Filho,Gustavo Y. Miyake,Carlos H. T. P. da Silva

Review Article

Signal Transduction through JAK-STAT and NF-κB Regulated Pim-1 Kinase: Novel Target for Anticancer Leads

Journal: Current Signal Transduction Therapy
Volume: 13 Issue: 2 Year: 2018 Page: 83-104
Author(s): Sisir Nandi,Mohd Salman,Ankita Sharma,Mohit Kumar

Research Article

Heterocyclization of Thiophenes Derived from Estrone Followed by Cytotoxic, HTRF Kinase and Pim-1 Kinase Evaluations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 1711-1728
Author(s): Mahmoud A. Abdelaziz Mahmoud,Rafat Milad Mohareb,Mashari A. Al-Sharif

Research Article

Propofol Protects Against TNF-α-induced Blood-brain Barrier Disruption via the PIM-1/eNOS/NO Pathway

Journal: Current Neurovascular Research
Volume: 17 Issue: 4 Year: 2020 Page: 471-479
Author(s): Yan Lu,Zhendong Xu,Fuyi Shen,Rong Lin,Haibing Li,Xiang Lv,Zhiqiang Liu

Research Article

The Uses of Dimedone for the Synthesis of Thiophene, Thiazole and Annulated Derivatives with Antitumor, Pim-1 Kinase Inhibitions, PAINS Evaluations and Molecular Docking

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 0 Year: 2021 Page: 1-20
Author(s): Wagnat W. Wardakhan,Amira M. Elmetwally,Abeer A. Mohamed,Rafat M. Mohareb

Review Article

Abnormal Signal Transduction via Over-expression of Pim-1 Regulated Senescence, Cell Cycle, Apoptosis and Metastatic Invasion: Novel Anticancer Targets and Their Potent Inhibitors from Marine Sources

Journal: Current Signal Transduction Therapy
Volume: 15 Issue: 1 Year: 2020 Page: 3-11
Author(s): Ankita Sharma,Sisir Nandi

Research Article

Design, Synthesis, Molecular Docking, and Biological Studies of New Heterocyclic Compounds Derived from β-Diketones as Novel EGFR and Pim-1 Inhibitors Endowed with AntitumorActivity

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 22 Issue: 1 Year: 2022 Page: 2558-2576
Author(s): Rafat Milad Mohareb,Noha M. Asaad Bagato,Ibrahim Taha Radwan

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