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Search Result "17,20-lyase"

Synthesis, Biochemical Evaluation and Rationalisation of the Inhibitory Activity of a Series of 4-Substituted Phenyl Alkyl Triazole-Based Compounds as Potential Inhibitors of 17α-Hydroxylase/17,20-Lyase (P45017α)

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 7 Year: 2007 Page: 479-483
Author(s): Caroline P. Owen, Sachin Dhanani, Chirag H. Patel, Sabbir Ahmed

Synthesis, Biochemical Evaluation and Rationalisation of the Inhibitory Activity of a Range of Derivatives of 2-imidazol-1-yl-1-phenyl-ethanone as Potential Novel Inhibitors of 17α-hydroxylase/17,20-lyase (P-45017α)

Journal: Letters in Drug Design & Discovery
Volume: 8 Issue: 6 Year: 2011 Page: 516-522
Author(s): Kruti Shah, Baljeet Jandu, Ammara Abdullah, Sabbir Ahmed

Synthesis and Biochemical Evaluation of a Range of Non-Substituted Phenyl Alkyl Triazole-Based Compounds as Potential Inhibitors of the Enzyme Complex 17α -Hydroxylase/17,20-Lyase (P45017α)

Journal: Letters in Drug Design & Discovery
Volume: 3 Issue: 1 Year: 2006 Page: 761-765
Author(s): Caroline P. Owen, Chirag H. Patel, Sachin Dhanani, Sabbir Ahmed

Synthesis and Biochemical Evaluation of a Range of 4-(n-alkanesulfonate) benzyl Imidazole-Based Compounds as Inhibitors of Rat Testicular 17α-hydroxylase/17,20-lyase (P450_17α) in the Treatment of Hormone- Dependent Prostate Cancer

Journal: Letters in Drug Design & Discovery
Volume: 11 Issue: 8 Year: 2014 Page: 1000-1009
Author(s): Pallav S. Shah,Imran Shahid,Wai-Yee Lee,Caroline P. Owen,Sabbir Ahmed

Synthesis and Biochemical Evaluation of a Range of 2-, 3- and 4-Substituted Derivatives of Benzyl Imidazole-Based Compounds as Probes of the Active Site of 17α-hydroxylase/17,20-Lyase (P45017α)

Journal: Letters in Drug Design & Discovery
Volume: 6 Issue: 7 Year: 2009 Page: 524-530
Author(s): Sabbir Ahmed, Imran Shahid, Kishore K. Bhatti, Wai-Yee Lee, Caroline P. Owen

Genetics, Structure, Function, Mode of Actions and Role in Cancer Development of CYP17

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 1 Year: 2014 Page: 66-76
Author(s): Tatyana. A Sushko,Andrei A. Gilep,Sergey A. Usanov

Review Article

A Homodimer Model Can Resolve the Conundrum as to How Cytochrome P450 Oxidoreductase and Cytochrome b5 Compete for the Same Binding Site on Cytochrome P450c17

Journal: Current Protein & Peptide Science
Volume: 18 Issue: 5 Year: 2017 Page: 515-521
Author(s): Jessica K. Holien, Michael W. Parker, Alan J. Conley, Cynthia Jo Corbin, Raymond J. Rodgers, Lisandra L. Martin

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