Abstract
Computer-Aided Drug Discovery (CADD) has yielded remarkable
successes, transforming the pharmaceutical landscape. Notable achievements include
the development of kinase inhibitors for cancer treatment and repurposing of drugs for
emerging health crises like COVID-19. CADD's role in personalized medicine is
exemplified by tailored therapies for genetically defined patient groups in cancer
treatment. Moreover, CADD has enhanced drug development efficiency, minimizing
attrition rates and reducing costs for pharmaceutical companies. These successes
illustrate the pivotal role of CADD in addressing complex diseases, streamlining drug
development, and improving healthcare outcomes. Continuous advancements in
computational techniques and interdisciplinary collaboration promise further
breakthroughs in the field.
Keywords: Computer-aided, Drug discovery, Drug development, Pharmacophore analysis, Target identification, Virtual screening.