Abstract
Biotechnological advancements have started gaining importance for
subsidizing conventional breeding strategies to the latest cost-effective techniques that
enhance the yield and are robust. This effort aims at showcasing the different strategies
adapted to bring up the production curve in fisheries, poultry and livestock by using the
latest biotechnological assays and procedures. A better understanding of disease
resiliency in animals and increasing the growth rate of fish, domestic animals and
poultry birds can help cope with the increased demand for milk, meat, eggs and
proteins worldwide. The genome engineering tools, such as CRISPR-Cas9, single
nucleotide polymorphism, somatic cell nuclear transfer, zinc-finger nucleases, Sperm
Transfection–Assisted Gene Editing (STAGE) and cloning, possess the ability to alter
the genome either by knocking in or knocking out of the genes for better selection of
the breeds. Genomic estimated breeding values (GEBVs) are devised using the gene
markers without prior knowledge of the exact gene location across the chromosome.
These predictive values help in gene insertion or gene deletion in the host. The
breeding programmes initiative can bring up advantages by managing the resources and
growing the yield. The biotechnology applications should be incorporated with
progressing customary reproducing and improvement programs to meet the growing
challenge of feeding the population of 9 billion.
Keywords: CRISPR-cas9, Genomic estimated breeding values (GEBVs), Sperm transfection–assisted gene editing (STAGE).