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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Review Article

The Novel Medical Thermoresponsive Hydrogel Derived from Chitosan

Author(s): Ming Kong and Xiguang Chen*

Volume 22 , Issue 7 , 2018

Page: [620 - 627] Pages: 8

DOI: 10.2174/1385272821666170811111651

Price: $65


Background: Chitosan thermoresponsive hydrogel is non-covalent crosslinked intelligent hydrogel. The compositions of the hydrogel determine its gelling property associated with particular structure-interaction effects. Simple and mild preparations as well as desirable bioactivities allow chitosan thermoresponsive hydrogels extensively applied in drug delivery and tissue engineering, especially the exciting proceeding in enzyme-free cell harvest and vascular embolic agent.

Objective: This paper reviewed the classification of chitosan thermoresponsive hydrogels based on different components, emphasizing their gelling capacities, mechanism and applications in biomedical areas.

Keywords: Chitosan, thermoresponsive hydrogel, sol-gel reversible, drug delivery, tissue engineering, cell culture, wound dressing, embolic agent.

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