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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

Cyclic Dipeptides: Secondary Metabolites Isolated from Different Microorganisms with Diverse Biological Activities

Author(s): Aurelio Ortiz and Estibaliz Sansinenea*

Volume 24, Issue 25, 2017

Page: [2773 - 2780] Pages: 8

DOI: 10.2174/0929867324666170623092818

Price: $65


Cyclic dipeptides are the simplest peptide derivatives commonly found in nature. These chiral molecules are easily synthesized from readily available α-amino acids using a simple methodology. They are privileged structures with the ability to bind to a wide range of receptors and have a broad variety of biological and pharmacological activities. We will give a brief overview of their status giving and interesting reference list about the last works.

Keywords: Cyclic dipeptides, Secondary metabolites, Biological activities, diketopiperazines, cyclo(L-pro), natural compounds.

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